NIH U54 funding opportunities: Specialized Center Cooperative Agreement
5 NIH notices for U54 (Specialized Center Cooperative Agreement) are open and 4 forecast. A research center with several projects and shared cores, with...
- Open notices5
- Forecast4
- Projects funded under them4,929
Open NIH U54 notices
- Cancer Advancement through Partnerships in Research and Infrastructure (CAPRI) (U54 Clinical Trial Optional)
Open - Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
Open - George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional)
Open - Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)
Open - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Open
Forecast U54 notices
- Forecast to Publish a Funding Opportunity Announcement for Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)
Forecast - Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
Forecast - Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)
Forecast - Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed)
Forecast
Institutes that fund U54 projects under these notices
| Institute or center | Projects |
|---|---|
| National Cancer Institute (NCI) | 807 |
| National Heart Lung and Blood Institute (NHLBI) | 494 |
| National Institute of General Medical Sciences (NIGMS) | 454 |
| National Institute on Aging (NIA) | 448 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 408 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 345 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 298 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 237 |
| National Institute of Mental Health (NIMH) | 232 |
| National Institute on Drug Abuse (NIDA) | 219 |
Closed U54 notices
- RFA-RM-27-014: Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)
- RFA-DA-27-015: Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trial Not Allowed)
- RFA-DK-27-127: Cooperative Centers for Experimental Hematology (CCEHs) (U54- Clinical Trial Not Allowed)
- RFA-CA-27-012: Metastasis Research Network (U54 Clinical Trial Not Allowed)
- RFA-HL-27-009: Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)
- RFA-DA-26-020: Dynamic and Adaptable Infrastructure for Drug Development and Outreach to Aid the Research Community in Advancing Medication Repurposing and Repositioning Efforts for Substance Use Disorders (SUDs) (U54 - Clinical Trials Not Allowed)
- PAR-25-438: Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
- RFA-OD-22-014: Specialized Centers of Research Excellence (SCORE) on Sex Differences (U54 Clinical Trial Optional)
- PA-23-189: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
- PAR-23-308: Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional)
- PAR-22-114: Administrative Supplements to Support Cancer Disparity Collaborative Research (Clinical Trial Optional)
- RFA-DE-25-003: TMD Collaborative for IMproving PAtient-Centered Translational Research (TMD IMPACT) (U54 Clinical Trial Optional)
- PAR-24-305: Centers for Precision Disease Modeling (U54) (Clinical Trials Not Allowed)
- RFA-DA-25-056: Establishing a Center for the Advancement of Substance Use Disorder (SUD) Pharmacotherapeutics through Training and Preclinical Support (U54 Clinical Trials Not Allowed)
- RFA-MD-24-012: Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)
- RFA-DK-25-016: Polycystic Kidney Disease Core Centers (U54 Clinical Trial Not Allowed)
- RFA-CA-24-020: Specialized Programs of Research Excellence (SPOREs) in Cancer Health Disparities and Minority Health (CHD-MH) (U54 Clinical Trial Optional)
- PAR-24-206: Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)
- RFA-AI-23-077: Center of Excellence for Systems Modeling of Infection and Immunity across Biological Scales (U54 Clinical Trial Not Allowed)
- RFA-AG-25-002: Consortium for Palliative Care Research Across the Lifespan (U54 Clinical Trial Optional)
- PA-21-268: Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
- RFA-HG-22-026: Diversity Centers for Genome Research (U54 Clinical Trials Optional)
- PAR-22-077: NIA Renewal and Revision Cooperative Agreements in AD/ADRD Research (U54 Clinical Trial Optional)
- RFA-AG-24-040: Microphysiological Systems to Advance Precision Medicine for AD/ADRD Treatment and Prevention (U54 Clinical Trial Not Allowed)
- RFA-OD-24-005: Down Syndrome Clinical Cohort Coordinating Center (DS-4C) for the INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) (U54 Clinical Trial Not Allowed)
- RFA-MD-24-001: Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)
- RFA-AG-24-030: Consortium for Economic Research on AD/ADRD Prevention, Treatment, and Care Coordinating Center (U54 Clinical Trial Optional)
- RFA-RM-23-019: Human Virome Characterization Centers (U54 Clinical Trial Not Allowed)
- RFA-AG-24-033: State Dementia Care Research Center (U54 Clinical Trial Not Allowed)
- RFA-CA-23-008: Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional)
- RFA-AG-24-009: Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) Real-World Data Platform (U54 Clinical Trial Optional)
- RFA-RM-23-002: Integration and Coordination Center for the Common Fund Data Ecosystem (U54 Clinical Trial Not Allowed)
- RFA-NS-24-022: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRCs) (U54 Clinical Trial Optional)
- RFA-DK-22-511: Limited Competition for the Continuation of the Rare and Atypical Diabetes NeTwork (RADIANT) Specialized Study Centers (U54 - Clinical Trial Not Allowed)
- RFA-MD-23-001: Research Centers in Minority Institutions (RCMI) (U54 Clinical Trial Optional)
- RFA-AG-24-024: Understanding the Supply of Professional Dementia Care Providers and Their Decisions (U54 Clinical Trial Not Allowed)
- PAR-22-203: Point-of-Care Technologies Research Network: Technology Research and Development Centers (TRDC) (U54 Clinical Trial Optional)
- PAR-22-249: Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional)
- RFA-AG-23-018: Understanding the Supply of Professional Dementia Care Providers and Their Decisions (U54 Clinical Trial Not Allowed)
- RFA-HD-23-035: Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional)
- RFA-DK-22-007: George M. O'Brien Kidney National Resource Centers (U54 - Clinical Trial Not Allowed)
- RFA-CA-22-055: Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT) Centers (U54 Clinical Trial Not Allowed)
- RFA-CA-22-019: Global Implementation Science for Equitable Cancer Control (GlobalISE Cancer Control, U54 Clinical Trial Optional)
- RFA-CA-22-012: Patient Derived Xenograft (PDX) Development and Trial Centers (PDTCs) Network (U54 Clinical Trial Not Allowed)
- RFA-CA-21-048: Research Centers for Cancer Systems Biology (U54 Clinical Trial Not Allowed)
- RFA-CA-22-046: Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
- RFA-CA-22-007: Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional)
- RFA-OD-22-003: Center for Coordination of Analysis, Science, Enhancement, and Logistics (CASEL) in Tobacco Regulatory Science (U54 Clinical Trial Not Allowed)
- RFA-OD-22-004: Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54 Clinical Trial Optional)
- RFA-RM-22-008: NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Cohort (U54 Clinical Trial Optional)
- RFA-CA-22-015: Cancer Control Research in Persistent Poverty Areas (U54 Clinical Trial Optional)
- RFA-NS-22-019: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRCs) (U54, Basic Experimental Studies Involving Humans Allowed)
- RFA-RM-22-002: SPARC VNS Endpoints from Standardized Parameters (VESPA) (U54 Clinical Trial Required)
- RFA-CA-22-011: U.S. and Low- and Middle-Income Country (LMIC) HIV-Associated Malignancy Research Centers (U54 Clinical Trial Optional)
- RFA-MD-22-002: Research Centers in Minority Institutions (RCMI) (U54 Clinical Trials Optional)
- RFA-RM-22-003: Cellular Senescence Network: Murine Tissue Mapping Centers (U54 - Clinical Trial Not Allowed)
- RFA-AA-21-015: Collaborative Partnership between Research Centers in Minority Institutions (RCMI) and Alcohol Research Centers (U54 Clinical Trial Optional)
- RFA-OD-21-010: Advancing Gender Inclusive Excellence (AGIE) Coordinating Center (U54 Clinical Trial Not Allowed)
- RFA-RM-21-026: Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed)
- RFA-CA-21-054: Translational and Basic Science Research in Early Lesions (TBEL) (U54 Clinical Trial Not Allowed)
- RFA-CA-21-040: Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
- RFA-CA-21-052: Acquired Resistance to Therapy Network (ARTNet; U54 Clinical Trial Not Allowed)
- PAR-21-314: Blueprint MedTech: Incubator Hubs (U54 Clinical Trial Not Allowed)
- RFA-AI-21-030: Centers for HIV Structural Biology (U54 Clinical Trial Not Allowed)
- RFA-CA-21-038: Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT) Centers (U54 Clinical Trial Not Allowed)
- RFA-RM-21-025: NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Cohort (U54 Clinical Trial Optional)
- RFA-RM-21-023: Integration, Dissemination, and Evaluation (BRIDGE) Center for the NIH Bridge to Artificial Intelligence (Bridge2AI) Program (U54 Clinical Trial Not Allowed)
- RFA-RM-21-001: Nutrition for Precision Health, powered by the All of Us Research Program: Artificial Intelligence for Multimodal Data Modeling and Bioinformatics Center (U54 Clinical Trial Not Allowed)
- RFA-RM-21-008: Cellular Senescence Network: Tissue Mapping Centers (U54 Clinical Trial Not Allowed)
Questions people ask
What is an NIH U54?
U54 is NIH's activity code for the Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Each notice sets its own budget limit, project length and due dates.
How many NIH U54 funding opportunities are open?
5 notices are open on Grants.gov, and 4 more are forecast, as of the latest data.