RFA-OD-22-004: Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54 Clinical Trial Optional)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.
National Institutes of Health offered grants of up to $4.0 million to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on July 14, 2022.
From the official notice on Grants.gov, last changed March 8, 2022. Checked November 7, 2026.
- Award ceiling$4.0 million
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU54
- Clinical trialsOptional
- Funded byNIDA, NCI
- Median yearly award$553,377
- Typical project length5 years
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
Projects funded under RFA-OD-22-004 were run by National Institute on Drug Abuse (NIDA, 4 projects) and National Cancer Institute (NCI, 3 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-OD-22-004 in the NIH Guide.
Key dates
| Posted | March 7, 2022 |
|---|---|
| Deadline | July 14, 2022 |
| Archived by Grants.gov | August 19, 2022 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $553,377; it allows up to $4.0 million per award.
- Most of the program's money (77% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for Tobacco Centers of Regulatory Science (TCORS) to support biomedical and behavioral research that will provide scientific data to inform regulation of tobacco products to protect public health. Research Projects must address the Research Objectives related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP).
Funded under RFA-OD-22-004 so far
NIH funded 7 projects under RFA-OD-22-004 in fiscal 2023 to 2026, at 7 institutions. The median yearly award was $553,377.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Modeling the Process of Nicotine Addiction among Youths and Young Adults and Its Potential Future Consequences | University of Michigan at Ann Arbor | 2026 | $425,244 |
| Project 2 | University of Southern California | 2026 | $683,287 |
| Career Enhancement Core | Ohio State University | 2026 | $208,360 |
| UNC Center of Tobacco Regulatory Science | Univ of North Carolina Chapel Hill | 2026 | $3.6 million |
| Addictive Threshold of Nicotine and the Impact of Sweeteners | Yale University | 2026 | $348,552 |
| AppalTRuST Project 1: Population based Cohort study of tobacco use prevalence in Appalachian KY | University of Kentucky | 2026 | $287,205 |
| Project 1: Translational Studies on Temperature and Solvent Effects on Electronic Cigarette-Derived Oxidants | Pennsylvania State Univ Hershey Med Ctr | 2026 | $431,705 |
Who has won Family Smoking Prevention and Tobacco Control Act Regulatory Research grants before
From fiscal 2021 to 2025, Family Smoking Prevention and Tobacco Control Act Regulatory Research (93.077) awarded $313 million across 176 grant awards, an average of $1.8 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 10 | $28.4 million |
| University of Southern California | California | 6 | $23.0 million |
| University of North Carolina at Chapel Hill | North Carolina | 11 | $20.9 million |
| Regents of the University of Michigan | Michigan | 3 | $20.3 million |
| The Ohio State University | Ohio | 9 | $18.9 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-OD-22-004 still open?
No. It closed on July 14, 2022.
Who can apply for Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54 Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Tobacco Centers of Regulatory Science (TCORS) for Research Relevant to the Family Smoking Prevention and Tobacco Control Act (U54 Clinical Trial Optional)?
Closed July 14, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $4.0 million each.
Who has been funded under RFA-OD-22-004?
NIH RePORTER lists 7 projects funded under RFA-OD-22-004 in fiscal 2023 to 2026, at 7 institutions. The most were at University of Michigan at Ann Arbor, University of Southern California, Ohio State University.
Who has won Family Smoking Prevention and Tobacco Control Act Regulatory Research grants before?
The largest recipients over five fiscal years were Yale Univ, University of Southern California, University of North Carolina at Chapel Hill. The program made 176 awards worth $313 million in that time.
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