NIH UM1 funding opportunities: Research Project with Complex Structure Cooperative Agreement
11 NIH notices for UM1 (Research Project with Complex Structure Cooperative Agreement) are open and 2 forecast. A large research project with several...
- Open notices11
- Forecast2
- Projects funded under them6,644
Open NIH UM1 notices
- Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)
Open Closes November 10, 2026 (3 days left) - Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)
Open Closes November 10, 2026 (3 days left) - Cellular Senescence Network (SenNet): Discovery, Validation Centers (UM1 Clinical Trials Not Allowed)
Open - Cellular Senescence Network (SenNet): SenNet Data Coordination and Integration Center (SenNet DCIC) (UM1 Clinical Trials Not Allowed)
Open - Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)
Open - Computational Modeling and Analysis of the Impact of Genomic Variation on Function (UM1, Clinical Trial Not Allowed)
Open - Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)
Open - Immune Tolerance Network (UM1 Clinical Trial Required)
Open - Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
Open - Clinical and Translational Science Award (UM1 Clinical Trial Optional)
Open - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Open
Forecast UM1 notices
- Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed)
Forecast - Somatic Mosaicism across Human Tissues (SMaHT) Program: National Somatic Mosaicism Commons Data Analysis & Organizational Center (UM1 Clinical Trial Not Allowed)
Forecast
Institutes that fund UM1 projects under these notices
| Institute or center | Projects |
|---|---|
| National Cancer Institute (NCI) | 985 |
| National Heart Lung and Blood Institute (NHLBI) | 731 |
| National Institute of General Medical Sciences (NIGMS) | 590 |
| National Institute on Aging (NIA) | 578 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 536 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 531 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 449 |
| National Institute on Drug Abuse (NIDA) | 310 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 295 |
| National Institute of Mental Health (NIMH) | 291 |
Closed UM1 notices
- RFA-HG-24-026: Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1), Clinical Trial Optional
- RFA-CA-27-016: The Experimental Therapeutics Clinical Trials Network (ETCTN) Lead Academic Organizations (UM1 Clinical Trial Required)
- RFA-RM-24-010: Complement-ARIE New Approach Methodologies (NAMs) Technology Development Centers (UM1 Clinical Trial Optional)
- PA-23-189: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)
- RFA-DA-25-025: HEAL Initiative: JCOIN Phase II Clinical Research Hubs (UM1 Clinical Trial Required)
- RFA-CA-24-028: Limited Competition: AIDS Malignancy Consortium (AMC; UM1 Clinical Trial Required)
- RFA-MH-22-245: BRAIN Initiative: Engineering and optimization of molecular technologies for functional dissection of neural circuits (UM1 Clinical Trial Not Allowed)
- PAR-21-293: Clinical and Translational Science Award (UM1 Clinical Trial Optional)
- RFA-DA-25-015: Single Source: Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Coordination, Analysis, and Scientific Outreach (UM1 Clinical Trial Not Allowed)
- RFA-AI-24-011: Tailoring HIV Curative Strategies to the Participant (UM1 Clinical Trial Not Allowed)
- PA-21-268: Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
- RFA-CA-23-043: Single Source: AIDS and Cancer Specimen Resource (ACSR; UM1 Clinical Trials Not Allowed)
- RFA-CA-23-037: Next Generation Chemistry Centers for Fusion Oncoproteins (UM1 Clinical Trial Not Allowed)
- RFA-CA-24-007: Single Source: Pediatric Early Phase Clinical Trials Network (PEP-CTN; UM1 Clinical Trial Required)
- RFA-DA-24-068: HEAL Initiative: Justice Community Overdose Innovation Network (JCOIN) - Phase II Methodology and Advanced Analytics Resource Center (UM1 Clinical Trial Not Allowed)
- RFA-DA-24-023: Ending the HIV Epidemic: Focus on Justice Populations with SUD-Data Coordination and Dissemination Center (UM1 Clinical Trial Optional)
- RFA-HG-23-024: Limited Competition: High Quality Reference Genomes (UM1 Clinical Trial Not Allowed)
- RFA-CA-23-024: Limited Competition: Cooperative Human Tissue Network (CHTN; UM1 Clinical Trial Not Allowed)
- RFA-NS-22-048: BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Comprehensive Centers for Mouse Brain (UM1 Clinical Trial Not Allowed)
- RFA-NS-22-047: BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Comprehensive Centers for Human and Non-Human Primate Brain (UM1 Clinical Trial Not Allowed)
- RFA-AI-22-077: Consortium for Food Allergy Research: Leadership Center (UM1 Clinical Trial Required)
- RFA-AI-22-071: Autoimmunity Centers of Excellence, Clinical Research Program (UM1 Clinical Trial Required)
- RFA-HL-24-001: Pediatric Heart Network Clinical Research Centers (UM1 Clinical Trial Optional)
- RFA-AI-22-059: Consortium for Design of TB Drug Regimens (UM1 Clinical Trial Not Allowed)
- RFA-MH-22-290: BRAIN Initiative Cell Atlas Network (BICAN): Comprehensive Center on Human and Non-human Primate Brain Cell Atlases (UM1 Clinical Trial Not Allowed)
- RFA-DA-23-011: Registry of Medical Cannabis Use and Health Outcomes (UM1 - Clinical Trial Optional)
- RFA-RM-22-010: Somatic Mosaicism across Human Tissues (SMaHT) Program: Data Analysis Center (UM1 Clinical Trial Not Allowed)
- RFA-RM-22-013: Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed)
- RFA-AI-21-060: SUNBEAM - Analysis and Bioinformatics Center (ABC) (UM1 Clinical Trial Not Allowed)
- RFA-MH-21-235: BRAIN Initiative Cell Atlas Network (BICAN): Comprehensive Center on Human and Non-human Primate Brain Cell Atlases (UM1 Clinical Trial Not Allowed)
- RFA-HG-21-029: Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase 1: Data Production Research and Development Centers (UM1)(Clinical trials not allowed)
- RFA-HG-21-036: Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1) Clinical Trial Not Allowed
- RFA-HG-21-037: Limited Competition: Knockout Mouse Phenotyping Project Data Coordination Center and Database (UM1 Clinical Trial Not Allowed)
- RFA-AI-21-039: Consortium for Innovative HIV/AIDS Vaccine and Cure Research (UM1 Clinical Trial Not Allowed)
Questions people ask
What is an NIH UM1?
UM1 is NIH's activity code for the Research Project with Complex Structure Cooperative Agreement. A large research project with several connected parts, with substantial NIH involvement. Each notice sets its own budget limit, project length and due dates.
How many NIH UM1 funding opportunities are open?
11 notices are open on Grants.gov, and 2 more are forecast, as of the latest data.