PA-21-268: Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
Closed
This grant is closed. A newer notice from the same program is open now: Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) (PA-24-254). Status: Due dates in the notice, expires July 12, 2027. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on June 30, 2024.
From the official notice on Grants.gov, last changed June 30, 2021. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR01 / R21 / K01 / R35 / K08 / K23 / U01 / R03 / RF1 / R37 / R33 / R15 / R00 / K99 / R25 / R34 / K24 / DP5 / R61 / UH3 / DP2 / R13 / K00 / F30 / K25 / F32 / K76 / U24 / F31 / K02 / UG1 / UG3 / R24 / RM1 / D43 / R50 / U54 / R43 / UM1 / K07 / UF1 / P01 / K22 / R44 / DP1 / OT2 / UH2 / P2C / K43 / T34 / RC2 / G08 / U10 / K18 / UE5 / G11 / U2R / U34 / U13
- Clinical trialsOptional
- Funded byNCI, NHLBI, NIA
- Median yearly award$364,574
- Typical project length4.5 years
- R01, Research Project Grant. NIH's standard grant for a defined research project led by a named investigator, usually for up to five years. Other open R01 notices.
- R21, Exploratory/Developmental Research Grant. Early, exploratory ideas that may not have preliminary data yet, usually for up to two years. Other open R21 notices.
- K01, Mentored Research Scientist Career Development Award. Protected time with a mentor for a researcher building an independent career. Other open K01 notices.
- R35, Outstanding Investigator Award. Support for an investigator's whole research program rather than a single project (this includes MIRA awards). Other open R35 notices.
- K08, Mentored Clinical Scientist Research Career Development Award. Protected time with a mentor for a clinician doing laboratory or translational research. Other open K08 notices.
- K23, Mentored Patient-Oriented Research Career Development Award. Protected time with a mentor for a clinician doing research with patients. Other open K23 notices.
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
- R03, Small Grant. A small, short project such as pilot work, a feasibility study, secondary data analysis or a new method, usually for up to two years. Other open R03 notices.
- R33, Exploratory/Developmental Grant Phase II. The second phase of a phased award, usually following an R61 or R21 phase. Other open R33 notices.
- R15, Research Enhancement Award. Small research projects at institutions that receive little NIH funding, with students taking part in the research. Other open R15 notices.
- R00, Research Transition Award. The independent phase of the K99/R00 Pathway to Independence award. Other open R00 notices.
- K99, Pathway to Independence Award. A mentored postdoctoral phase that leads into the independent R00 phase. Other open K99 notices.
- R25, Education Project. Research education programs: courses, research experiences and outreach that prepare people for research careers. Other open R25 notices.
- R34, Planning Grant. Planning a clinical trial: design, protocol and feasibility work before the trial itself. Other open R34 notices.
- K24, Midcareer Investigator Award in Patient-Oriented Research. Time for an established clinical investigator to do patient-oriented research and mentor others. Other open K24 notices.
- R61, Exploratory/Developmental Phase I. The first phase of a phased award. Moving on to the R33 phase depends on meeting agreed milestones. Other open R61 notices.
- UH3, Exploratory/Developmental Cooperative Agreement Phase II. The second phase of a phased cooperative agreement, usually following a UG3 or UH2 phase. Other open UH3 notices.
- DP2, NIH Director's New Innovator Award. Support for an early-stage investigator's highly innovative project. Other open DP2 notices.
- R13, Support for Conferences and Scientific Meetings. Costs of a scientific conference or meeting. Other open R13 notices.
- K00, Postdoctoral Transition Award. The postdoctoral phase of the F99/K00 award. Other open K00 notices.
- K25, Mentored Quantitative Research Development Award. Mentored time for researchers from quantitative fields such as engineering or mathematics to move into health research. Other open K25 notices.
- F32, Ruth L. Kirschstein Postdoctoral Individual NRSA. A fellowship for a postdoctoral researcher's training. Other open F32 notices.
- U24, Resource-Related Research Project Cooperative Agreement. Shared research resources such as data centers or coordinating centers, with substantial NIH involvement. Other open U24 notices.
- F31, Ruth L. Kirschstein Predoctoral Individual NRSA. A fellowship for a PhD student's research training. Other open F31 notices.
- UG3, Exploratory/Developmental Phase I Cooperative Agreement. The first phase of a phased cooperative agreement. Moving on to the UH3 phase depends on meeting agreed milestones. Other open UG3 notices.
- R24, Resource-Related Research Project. Resources that serve a research field, such as databases, tools or shared methods. Other open R24 notices.
- RM1, Research Project with Complex Structure. A large research project with several connected parts under one award. Other open RM1 notices.
- D43, International Research Training Grant. Research training programs for scientists from low- and middle-income countries. Other open D43 notices.
- R50, Research Specialist Award. Salary support for career research scientists who work in a research team without leading it. Other open R50 notices.
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
- R43, Small Business Innovation Research (SBIR) Phase I. A small business tests the feasibility of a technology or product. Other open R43 notices.
- UM1, Research Project with Complex Structure Cooperative Agreement. A large research project with several connected parts, with substantial NIH involvement. Other open UM1 notices.
- P01, Research Program Project Grant. Several related research projects around one theme, with shared core facilities. Other open P01 notices.
- K22, Career Transition Award. Support for moving from a postdoctoral position to an independent research job. Other open K22 notices.
- R44, Small Business Innovation Research (SBIR) Phase II. Full research and development of an SBIR project after Phase I (or both phases at once, called Fast Track). Other open R44 notices.
- DP1, NIH Director's Pioneer Award. Support for an exceptionally creative scientist's high-risk, high-impact ideas. Other open DP1 notices.
- K43, Emerging Global Leader Award. Career development for researchers in low- and middle-income countries. Other open K43 notices.
- K18, Research Career Enhancement Award. Time for an established investigator to learn new skills or move into a new field. Other open K18 notices.
- UE5, Education Project Cooperative Agreement. Research education programs, with substantial NIH involvement. Other open UE5 notices.
- U34, Planning Cooperative Agreement. Planning a clinical trial, with substantial NIH involvement. Other open U34 notices.
Projects funded under PA-21-268 were run by National Cancer Institute (NCI, 469 projects), National Heart Lung and Blood Institute (NHLBI, 346 projects), National Institute on Aging (NIA, 283 projects) and National Institute of Allergy and Infectious Diseases (NIAID, 270 projects), and 21 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PA-21-268 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PA-24-254 | July 11, 2024 | Due dates in the notice, expires July 12, 2027 | Open |
Key dates
| Posted | June 30, 2021 |
|---|---|
| Deadline | June 30, 2024 |
| Archived by Grants.gov | August 5, 2024 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Most of the money in the 32 programs behind this notice (71% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Institutes of Health (NIH) hereby notify recipient organizations holding specific types of NIH grants, listed in the full Funding Opportunity Announcement (FOA), that applications for change of recipient organization may be submitted to this FOA. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests (as described in Section 8.1.2.7 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award. Although requests for change of recipient organization may be submitted through this FOA, there is no guarantee that an award will be transferred to the new organization. All applicants are encouraged to discuss potential requests with the awarding IC before submission.
Funded under PA-21-268 so far
NIH funded 3,069 projects under PA-21-268 in fiscal 2017 to 2026, at 389 institutions. The median yearly award was $364,574.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Determinants of reservoir contraction and expansion in vivo, ex vivo, and in vitro | Emory University | 2026 | $648,378 |
| Memory Care in Assisted Living: Does it Improve Quality Outcomes | Johns Hopkins University | 2026 | $736,033 |
| Microglial regulation of neuronal activity in TDP-43 neurodegeneration | University of Texas HLTH Sci Ctr Houston | 2026 | $711,702 |
| Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease | University of Tennessee Health Sci Ctr | 2026 | $549,829 |
| Investigating the Mechanism of Optic Nerve disorders associated with Down Syndrome | University of Alabama at Birmingham | 2026 | $478,880 |
| Mechanisms for cell signaling in the control of cardiomyogenesis | University of South Florida | 2025 | $411,977 |
| Fronto-thalamic interactions in value-based decision making under uncertainty | Children's Hosp of Philadelphia | 2025 | $249,000 |
| Enhanced Imaging of the Fetal Brain Microstructure | University of California-Irvine | 2025 | $469,574 |
Who has won Allergy and Infectious Diseases Research grants before
From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Fred Hutchinson Cancer Center | Washington | 85 | $938 million |
| Duke University | North Carolina | 230 | $781 million |
| University of California, Los Angeles | California | 138 | $745 million |
| The Johns Hopkins University | Maryland | 321 | $668 million |
| Emory University | Georgia | 282 | $650 million |
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
Who has won Cardiovascular Diseases Research grants before
From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Trustees of the University of Pennsylvania | Pennsylvania | 313 | $380 million |
| Brigham & Womens Hospital Inc | Massachusetts | 274 | $374 million |
| Regents of the University of Michigan | Michigan | 277 | $355 million |
| The Trustees of Columbia University in the City of New York | New York | 207 | $335 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 295 | $320 million |
Other programs behind this notice
- Biomedical Research and Research Training
- Diabetes, Digestive, and Kidney Diseases Extramural Research
- Extramural Research Programs in the Neurosciences and Neurological Disorders
- Mental Health Research Grants
- Drug Use and Addiction Research Programs
- Child Health and Human Development Extramural Research
- Trans-NIH Research Support
- Cancer Treatment Research
- Cancer Biology Research
- Cancer Cause and Prevention Research
- Vision Research
- National Center for Advancing Translational Sciences
- Cancer Centers Support Grants
- Cancer Detection and Diagnosis Research
- Arthritis, Musculoskeletal and Skin Diseases Research
- Alcohol Research Programs
- Human Genome Research
- Environmental Health
- Minority Health and Health Disparities Research
- Oral Diseases and Disorders Research
- Discovery and Applied Research for Technological Innovations to Improve Human Health
- Research Infrastructure Programs
- Cancer Research Manpower
- Cancer Control
- Nursing Research
- Research and Training in Complementary and Integrative Health
- Medical Library Assistance
- Lung Diseases Research
- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-24-254, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PA-21-268 still open?
No. It closed on June 30, 2024. A newer notice is open: PA-24-254, due dates in the notice, expires July 12, 2027.
Who can apply for Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)?
Closed June 30, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under PA-21-268?
NIH RePORTER lists 3,069 projects funded under PA-21-268 in fiscal 2017 to 2026, at 389 institutions. The most were at Emory University, University of Alabama at Birmingham, University of Pittsburgh at Pittsburgh.
Who has won Environmental Health grants before?
The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.
Similar open grants
- Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
- Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)
- Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
- Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
- Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)