FOR-MD-25-004: Forecast to Publish a Funding Opportunity Announcement for Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)
Forecast
This forecast is out of date. Its expected dates have passed and the agency has not posted the opportunity on Grants.gov. It may be delayed or cancelled; check the program's other opportunities below.
National Institutes of Health plans to offer grants to colleges and universities. It expects to make about 5 awards worth $22.0 million in total. It is a forecast: the notice is expected around September 24, 2025, with applications due around November 26, 2025.
From the official notice on Grants.gov, last changed June 10, 2025. Checked November 7, 2026.
- Total funding$22.0 million
- Expected awards5
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU54
- Clinical trialsOptional
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
Key dates
| Forecast posted | June 10, 2025 |
|---|---|
| Expected posting | September 24, 2025 |
| Expected deadline | November 26, 2025 |
| Expected award date | March 25, 2026 |
Add the deadline to your calendar or it to My grants.
Who can apply
This opportunity is open to colleges and universities.
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
To be eligible for this NOFO, the applicant institution must be a domestic institution located in the United States and its territories which: Has received an average of less than $50 million per year or less than $25 million per year of R01 total costs of NIH support for the past three fiscal years; Awards doctorate degrees in the health professions, or the sciences related to health
Is this a realistic fit?
- Most of the program's money (78% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The National Institute on Minority Health and Health Disparities intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to expand the national capacity for research in the health sciences. NIH established the Research Centers in Minority Institutions (RCMI) program in 1985 in response to Congressional interest to provide support to less research-intensive institutions that offer doctorate degrees in the health professions or in a health-related science. The primary goals of RCMI Specialized Center awards are to: (1) enhance institutional research capacity to conduct world-class basic biomedical, behavioral, population and/or clinical patient-centered or health services research; (2) enable all levels of investigators at the recipient institution to compete successfully for extramural support, especially from NIH, for research on diseases and conditions that disproportionately impact populations that experience health disparities; (3) facilitate research career development and enhancement for post-doctoral fellows, junior faculty members, and other early-stage investigators; (4) enhance the tools for, and conduct of, biomedical research; and (5) establish sustainable partnerships with community-based organizations to promote research efforts and the dissemination of research findings. The RCMI program allows flexibility at the applicant institution with respect to the types of research resources required to accomplish research and investigator development goals. The most important criterion for any component in the proposed Center is the extent to which the activity or resource will enable the institution to achieve the stated goals and objectives. The following components are required for each RCMI Center: Overall Administrative Core Research Capacity Core Investigator Development Core` Community Engagement Core Research Project(s): Maximum three projects Centers are expected to support up to three research projects with an explicit focus on one or more of the following scientific areas: 1) basic biomedical research, and/or 2) behavioral or social science research or population science, and/or 3) clinical or health services research. Successful projects will emphasize research that directly interacts with participants. To receive the maximum Center budget, applicants must propose one research project in each of the three scientific focus areas. Applications are not being solicited at this time.
Who has won Minority Health and Health Disparities Research grants before
From fiscal 2021 to 2025, Minority Health and Health Disparities Research (93.307) awarded $2.0 billion across 1,237 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Johns Hopkins University | Maryland | 37 | $69.3 million |
| The Trustees of Columbia University in the City of New York | New York | 25 | $59.1 million |
| University of Hawaii | Hawaii | 18 | $52.8 million |
| The Regents of the University of California, San Francisco | California | 24 | $49.5 million |
| The Morehouse School of Medicine, Inc. | Georgia | 4 | $44.1 million |
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to Nathan Stinson, Jr., PhD, MD, MPH, National Institute on Minority Health and Health Disparities (NIMHD), stinsonn@mail.nih.gov, 301-594-8704.
Questions people ask
Is FOR-MD-25-004 still open?
Not yet. It is a forecast: expected deadline November 26, 2025.
Who can apply for Forecast to Publish a Funding Opportunity Announcement for Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)?
National Institutes of Health accepts applications from colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for Forecast to Publish a Funding Opportunity Announcement for Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)?
Expected deadline November 26, 2025. Confirm the date and time in the official notice on Grants.gov.
How much funding is available?
About $22.0 million in total across about 5 awards.
Who has won Minority Health and Health Disparities Research grants before?
The largest recipients over five fiscal years were The Johns Hopkins University, The Trustees of Columbia University in the City of New York, University of Hawaii. The program made 1,237 awards worth $2.0 billion in that time.
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