RFA-DK-28-314: George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional)
Open
National Institutes of Health is offering grants of up to $750,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 5 awards worth $5.2 million in total. Applications close on February 1, 2027.
From the official notice on Grants.gov, last changed November 3, 2026. Checked November 7, 2026.
- Award ceiling$750,000
- Total funding$5.2 million
- Expected awards5
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU54
- Clinical trialsOptional
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
Application due dates, page limits and budget limits are set in the notice. Read RFA-DK-28-314 in the NIH Guide.
Key dates
| Posted | November 3, 2026 |
|---|---|
| Deadline | February 1, 2027 |
| Archived by Grants.gov | April 1, 2027 |
Add the deadline to your calendar or it to My grants.
Who can apply
This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Is this a realistic fit?
- No cost sharing or match is required.
What the grant funds
This Notice of Funding Opportunity (NOFO) seeks support for continuation of the NIDDK George M. O'Brien Urology Cooperative Research Centers (U54). The Urology Cooperative Research Centers foster impactful, multi-disciplinary research through collaborations within and outside the Centers and serve as a national resource for the urology research community.
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to National Institutes of Health, NIDDK_KUH@nih.gov, 301-402-2541.
Questions people ask
Is RFA-DK-28-314 still open?
Yes. Closes February 1, 2027 (86 days left).
Who can apply for George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional)?
National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional)?
Closes February 1, 2027 (86 days left). Confirm the date and time in the official notice on Grants.gov.
How much funding is available?
Awards of up to $750,000 each. About $5.2 million in total across about 5 awards.
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