RFA-RM-23-019: Human Virome Characterization Centers (U54 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 17, 2023.
From the official notice on Grants.gov, last changed September 14, 2023. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU54
- Clinical trialsNot allowed
- Funded byNIA
- Median yearly award$810,266
- Typical project length5 years
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
Projects funded under RFA-RM-23-019 were run by National Institute on Aging (NIA, 5 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-RM-23-019 in the NIH Guide.
Key dates
| Posted | September 13, 2023 |
|---|---|
| Deadline | November 17, 2023 |
| Archived by Grants.gov | December 23, 2023 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The RFA will solicit applications for the Human Virome Program under the NIH Common Fund to establish multicomponent Virome Centers that will focus on the identification and characterization of the human virome in longitudinal and diverse cohorts across several body sites and tissues. The multicore structure of each center will allow for specialized and broad expertise in isolating viruses (circulating, proviral, integrated forms) and a coordinated, and comprehensive research program for recruiting diverse participants, collecting and analyzing many types of biospecimens, standardizing and analyzing center data, and addressing ethical, social and legal implications of human virome research. The Centers will also work collaboratively across the program consortium of separately awarded investigative teams in the coordination and management of consortium policies and practices. Similar to other U54 initiatives, the virome centers have unique objectives and specific review criteria and core specifications outlined in the RFA, and currently, there are no existing study sections with the necessary expertise to review this complex program.
Funded under RFA-RM-23-019 so far
NIH funded 5 projects under RFA-RM-23-019 in fiscal 2025 to 2026, at 5 institutions. The median yearly award was $810,266.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Biospecimen Collection | Vanderbilt University Medical Center | 2026 | $1.2 million |
| Human Virome Characterization Center for the Oral-Gut-Brain Axis | University of California Los Angeles | 2026 | $811,999 |
| Ethical, Legal, Social Implication Core | University of Pennsylvania | 2026 | $235,049 |
| Biospecimen Collection Core: Leveraging existing and prospectively collecting specimens in a diverse cohort | Broad Institute, Inc. | 2026 | $1.9 million |
| VAST Center: Viromes Across Space(s) and Time | Stanford University | 2026 | $513,515 |
Who has won Trans-NIH Research Support grants before
From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Duke University | North Carolina | 66 | $219 million |
| The Leland Stanford Junior University | California | 104 | $176 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 82 | $154 million |
| The Johns Hopkins University | Maryland | 95 | $152 million |
| Yale Univ | Connecticut | 85 | $149 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-RM-23-019 still open?
No. It closed on November 17, 2023.
Who can apply for Human Virome Characterization Centers (U54 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Human Virome Characterization Centers (U54 Clinical Trial Not Allowed)?
Closed November 17, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-RM-23-019?
NIH RePORTER lists 5 projects funded under RFA-RM-23-019 in fiscal 2025 to 2026, at 5 institutions. The most were at Vanderbilt University Medical Center, University of California Los Angeles, University of Pennsylvania.
Who has won Trans-NIH Research Support grants before?
The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.
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