RFA-RM-21-026: Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 19, 2021.
From the official notice on Grants.gov, last changed September 14, 2021. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU54
- Clinical trialsNot allowed
- Funded byNHLBI, NIDDK, NIAMS
- Median yearly award$567,366
- Typical project length4.5 years
- U54, Specialized Center Cooperative Agreement. A research center with several projects and shared cores, with substantial NIH involvement. Other open U54 notices.
Projects funded under RFA-RM-21-026 were run by National Heart Lung and Blood Institute (NHLBI, 4 projects), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 2 projects), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, 2 projects) and National Human Genome Research Institute (NHGRI, 1 project), and 1 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-RM-21-026 in the NIH Guide.
Key dates
| Posted | September 14, 2021 |
|---|---|
| Deadline | November 19, 2021 |
| Archived by Grants.gov | December 25, 2021 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This FOA seeks to support state-of-the-art Tissue Mapping Centers (TMCs) that will serve as the core data generators for the HuBMAP Consortium by generating a high-resolution, multi-parameter, 3D atlas of a non-diseased human organ. Successful centers will build, benchmark, and standardize pipelines for generating, validating and analyzing data from multiplexed, high-throughput imaging and omics technologies. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation in order to build high-resolution maps. Centers will use these maps to provide new insights into intra-, inter- and extra- cellular organizational features that influence tissue function, vary across individuals or that change across the lifespan. By the end of four years of funding, a successful center will have created a significant number of high-resolution, multi-scale, multi-dimensional molecular, cellular and morphological maps from multiple donors that are integrated into a published reference atlas for that organ.
Funded under RFA-RM-21-026 so far
NIH funded 10 projects under RFA-RM-21-026 in fiscal 2022 to 2025, at 9 institutions. The median yearly award was $567,366.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Stanford Tissue Mapping Center | Stanford University | 2025 | $500,000 |
| Kidney single cell and spatial molecular atlas project - KIDSSMAP | Washington University | 2025 | $500,000 |
| Data Analysis Core | Vanderbilt University | 2025 | $249,115 |
| Multiscale, Multimodal Analysis of Skin and Spatial Cell Organization | Ge Medical Systems Information Technologies, Inc | 2025 | $749,994 |
| Multi-scale Spatial Mapping of Human Lymphatic Vessels | Beth Israel Deaconess Medical Center | 2025 | $1.3 million |
| Pregnant Female Reproductive Tissue Mapping Center | University of California, San Diego | 2025 | $101,133 |
| Data Analysis Core | Children's Hosp of Philadelphia | 2025 | $249,269 |
| Multi-Scale Multi-Modality High Resolution Mapping of the Adult Human Lung | University of Rochester | 2025 | $273,954 |
Who has won Trans-NIH Research Support grants before
From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Duke University | North Carolina | 66 | $219 million |
| The Leland Stanford Junior University | California | 104 | $176 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 82 | $154 million |
| The Johns Hopkins University | Maryland | 95 | $152 million |
| Yale Univ | Connecticut | 85 | $149 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-RM-21-026 still open?
No. It closed on November 19, 2021.
Who can apply for Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed)?
Closed November 19, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-RM-21-026?
NIH RePORTER lists 10 projects funded under RFA-RM-21-026 in fiscal 2022 to 2025, at 9 institutions. The most were at Stanford University, Washington University, Vanderbilt University.
Who has won Trans-NIH Research Support grants before?
The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.
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