Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

RFA-HD-23-035: Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional)

Closed Closed December 5, 2022 Opportunity RFA-HD-23-035

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $17.5 million to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on December 5, 2022.

From the official notice on Grants.gov, last changed August 11, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-HD-23-035 were run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, 12 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-HD-23-035 in the NIH Guide.

Key dates

PostedAugust 11, 2022
DeadlineDecember 5, 2022
Archived by Grants.govJanuary 10, 2023

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Funding Opportunity Announcement (FOA) invites applications to participate as a Research Center as part of the Maternal Health Research Centers of Excellence initiative. The purpose of this initiative is to generate innovative approaches to address preventable maternal mortality, decrease severe maternal morbidity, and promote maternal health equity in partnership with communities that are most affected (i.e., Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations). This initiative will use an integrated multi-level approach encompassing social and biobehavioral research strategies to address the multiple contributing factors that lead to adverse maternal health outcomes and health disparities. Significant contributing factors include comorbid conditions (e.g., hypertension, diabetes, mental illness, and substance use disorders) and social determinants of health, which include structural racism and health care system factors. The goal of this initiative is for trans-disciplinary researchers to conduct multi-layered novel research approaches that will have the potential to drastically reduce pregnancy-related and pregnancy-associated maternal deaths and decrease severe maternal morbidity. Studies may be interventional (including effectiveness, comparative effectiveness, optimization, or dissemination and implementation studies), or observational (including health services studies, natural experiments, policy analyses) and may assess both short-term and long-term maternal health outcomes. The Research Centers will be uniquely poised to collaborate on studies and projects with other networks and initiatives such as the NICHD Neonatal Research Network and the NICHD Maternal and Pediatric Precision in Therapeutics (MPRINT) initiative.

Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services.

Funded under RFA-HD-23-035 so far

NIH funded 12 projects under RFA-HD-23-035 in fiscal 2023 to 2026, at 12 institutions. The median yearly award was $605,272.

Recently funded projects
ProjectInstitutionFiscal yearAward
CORAL CENTER U54Morehouse School of Medicine2026$2.7 million
Early Career-CeNtered EnricHment to AdvaNce Research Careers in Maternal HEalth -ENHANCE-M U54Medical College of Wisconsin2026$179,411
Community Care Implementation to Reduce Maternal Health Disparities U54Jackson State University2026$1.2 million
Training and Education U54University of Pittsburgh at Pittsburgh2026$574,335
Food for Lifecourse Resilience in Maternal Security and Health (FLOURISH) U54University of Oklahoma HLTH Sciences Ctr2026$813,542
Multilevel community-centered intervention to reduce pregnancy related and associated morbidity and mortality (PRAMM) and disparities U54Henry Ford Health + Michigan State University Health Sciences2026$959,568
Reducing Rates of Cesarean Birth and Cesarean-Linked Hemorrhages through Improved Obstetric Care U54Stanford University2026$491,732
UIC Maternal Health Research Center of Excellence U54University of Illinois at Chicago2026$2.7 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before

From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan273$345 million
The Trustees of the University of PennsylvaniaPennsylvania187$272 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania209$238 million
The Washington UniversityMissouri187$227 million
The Regents of the University of California, San FranciscoCalifornia176$208 million

Top states: California ($1.2 billion), Massachusetts ($932 million), New York ($798 million), Pennsylvania ($762 million), Texas ($482 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-HD-23-035 still open?

No. It closed on December 5, 2022.

Who can apply for Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional)?

Closed December 5, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $17.5 million each.

Who has been funded under RFA-HD-23-035?

NIH RePORTER lists 12 projects funded under RFA-HD-23-035 in fiscal 2023 to 2026, at 12 institutions. The most were at Morehouse School of Medicine, Medical College of Wisconsin, Jackson State University.

Who has won Environmental Health grants before?

The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.

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