Biomedical Research and Research Training (93.859)
Biomedical Research and Research Training (Assistance Listing 93.859) is run by the National Institutes of Health, part of the Department of Health and Human Services. It awarded $15 billion in 11,631 grants from fiscal 2021 to 2025, about $1.3 million per award on average. 65 funding opportunities are open or forecast now.
The typical award was $911,823. Half of the 11,631 awards fell between $401,110 and $1.6 million, and they ranged from $0 to $28.9 million.
- Awarded, FY 2021 to 2025$15 billion
- Grant awards11,631
- Typical award$911,823
- Awarded in FY 2025$3.0 billion
- Size rank40 of 1,823
- Type of assistanceProject grants
Key findings
- Annual funding rose from $2.6 billion in fiscal 2021 to $3.0 billion in fiscal 2025.
- It is the 40th largest of 1,823 federal grant programs by five-year awards.
- The 20 largest recipients received 27% of the money.
- Awards went to recipients in 53 states and territories.
What the program funds
The National Institute of General Medical Sciences (NIGMS) supports basic research that increases our understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS also supports research in specific clinical areas that affect multiple organ systems: anesthesiology and peri-operative pain; clinical pharmacology common to multiple drugs and treatments; and injury, critical illness, sepsis, and wound healing. NIGMS-funded scientists investigate how living systems work at a range of levels—from molecules and cells to tissues and organs—in research organisms, humans, and populations. Additionally, to ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in supporting the training of future scientists and developing research capacity throughout the country.
Open and forecast opportunities
- Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)
- Medical Scientist Training Program (MSTP) (T32)
- Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)
- Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)
- National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)
- Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)
- Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
- A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)
- NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
- NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
- Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
- Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
- NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
- Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
- Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
- NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)
- Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
- Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
- NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
- Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences
- Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
- Focused Technology Research and Development (R01 Clinical Trial Not Allowed)
- Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
- NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
- NIH Research Project Grant (Parent R01 Clinical Trial Required)
Rules from the program listing
Who can apply
NIGMS trainees must be U.S. citizens, non-citizen nationals, or permanent residents.
What the money can and cannot pay for
NIGMS is organized into divisions that support research, research training, and research capacity building in a range of scientific fields. Division of Biophysics, Biomedical Technology, and Computational Biosciences: Facilitates advances in basic biomedical research by supporting the development of experimental and computational methods and tools for understanding biology; implementation of novel technologies and approaches in the study of macromolecular, organelle, and cellular structure and function; and application of innovative physical and theoretical methodologies, bioinformatics tools, and quantitative approaches to lay a foundation for advances in disease diagnosis, treatment, and prevention. Division of Genetics and Molecular, Cellular, and Developmental Biology: Supports research to understand the structure and function of cells and cellular components and the cellular and molecular mechanisms that underlie inheritance, gene expression, and development. In most cases, research whose overall goal is to gain knowledge about a specific organ or organ system or the pathophysiology, treatment, or cure of a specific disease or condition is not supported by this division. Division of Pharmacology, Physiology, and Biological Chemistry: Supports a broad spectrum of research aimed at improving the molecular-level understanding of biological processes and approaches to their control.
Matching requirements
This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.
Deadlines
Application due dates are provided in each notice of funding opportunity.
Award range and average, in the agency's words
$20,000 to $10,000,000.
Funding history and past recipients
From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.
Who usually wins
Colleges and universities received 80% of the money, nonprofits 12% and small businesses 3.5%.
| Recipient type | Awards | Amount | Share |
|---|---|---|---|
| Colleges and universities | 9,342 | $12 billion | 80% |
| Nonprofits | 1,210 | $1.8 billion | 12% |
| Other | 422 | $519 million | 3.5% |
| Small businesses | 612 | $507 million | 3.5% |
| Tribal governments and organizations | 24 | $16.8 million | 0.1% |
| State and local governments | 18 | $11.5 million | less than 0.1% |
| Businesses | 3 | $3.1 million | less than 0.1% |
By state
Each state below has its own page for this program, with its recipients and yearly totals.
| State | Awards | Amount |
|---|---|---|
| California | 1,811 | $2.1 billion |
| New York | 1,116 | $1.4 billion |
| Massachusetts | 881 | $971 million |
| Texas | 791 | $833 million |
| Pennsylvania | 589 | $680 million |
| Illinois | 447 | $569 million |
| North Carolina | 458 | $511 million |
| Michigan | 373 | $403 million |
| Maryland | 332 | $373 million |
| Connecticut | 267 | $338 million |
| Wisconsin | 240 | $311 million |
| Washington | 258 | $289 million |
| Georgia | 287 | $285 million |
| Ohio | 276 | $281 million |
| Florida | 263 | $274 million |
| Colorado | 246 | $259 million |
| New Jersey | 208 | $257 million |
| Tennessee | 234 | $256 million |
| Missouri | 206 | $240 million |
| Nebraska | 83 | $213 million |
| Rhode Island | 85 | $207 million |
| South Carolina | 105 | $204 million |
| Oklahoma | 85 | $196 million |
| Virginia | 183 | $191 million |
| Indiana | 178 | $189 million |
| Louisiana | 76 | $174 million |
| Delaware | 57 | $162 million |
| Oregon | 130 | $155 million |
| Kansas | 75 | $151 million |
| Kentucky | 72 | $151 million |
| New Hampshire | 67 | $150 million |
| Minnesota | 134 | $150 million |
| Arkansas | 57 | $135 million |
| Utah | 140 | $135 million |
| Arizona | 124 | $126 million |
| Maine | 54 | $121 million |
| West Virginia | 36 | $116 million |
| New Mexico | 69 | $115 million |
| Mississippi | 39 | $101 million |
| North Dakota | 31 | $99.9 million |
| Montana | 43 | $87.7 million |
| Puerto Rico | 57 | $84.5 million |
| Nevada | 35 | $79.0 million |
| Alabama | 85 | $78.9 million |
| Hawaii | 19 | $78.9 million |
| Iowa | 72 | $76.6 million |
| Vermont | 27 | $69.3 million |
| Idaho | 37 | $66.7 million |
| District of Columbia | 56 | $47.1 million |
| Alaska | 11 | $41.7 million |
| Wyoming | 9 | $39.8 million |
| South Dakota | 10 | $34.0 million |
| U.S. Virgin Islands | 3 | $1.6 million |