Federal grant programs / Department of Health and Human Services

Cancer Centers Support Grants (93.397)

Also known as Cancer Centers

• Awarded, FY 2021 to 2025$2.8 billion
• Grant awards330
• Typical award$5.8 million
• Awarded in FY 2025$592 million
• Size rank125 of 1,823
• Type of assistanceCooperative agreements, project grants

Key findings

• Annual funding rose from $525 million in fiscal 2021 to $592 million in fiscal 2025.
• It is the 125th largest of 1,823 federal grant programs by five-year awards.
• The 20 largest recipients received 50% of the money.
• Awards went to recipients in 41 states and territories.

What the program funds

To provide an organizational focus and stimulus for the highest quality cancer research that effectively promotes interdisciplinary cancer research aimed toward the ultimate goal of reducing cancer incidence, mortality and morbidity. The Cancer Center Support Grant (CCSG) provides the resources and infrastructure to facilitate the coordination of interdisciplinary programs across a broad spectrum of research from basic laboratory research to clinical investigation to population science. The CCSG supports salaries for scientific leadership of the Center, shared resources for funded center investigators, certain administrative costs, planning and evaluation, and developmental funds for new recruitments and feasibility studies.

From the federal Assistance Listing. Read the full listing on SAM.gov.

Open and forecast opportunities

• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
  Open · Due dates in the notice, expires July 12, 2027
• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
  Open · Due dates in the notice, expires July 17, 2027
• Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
  Open · Due dates in the notice, expires May 4, 2028
• Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)
  Open · Due dates in the notice, expires September 7, 2028
• Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
  Open · Due dates in the notice, expires September 25, 2028
• NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)
  Open · Due dates in the notice, expires May 7, 2029
• NCI Research Specialist Award for Core and Laboratory-based Scientists (R50 Clinical Trial Not Allowed)
  Forecast · Expected deadline November 20, 2026
• Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
  Forecast · Expected deadline January 25, 2027
• Investigator-Focused Award (Parent R35)
  Forecast · Expected deadline October 4, 2027

Rules from the program listing

Who can apply

Any nonprofit institution within the United States with a peer-reviewed cancer research base of 4.0 million dollars in direct costs may apply for a Cancer Center Support Grant.

What the money can and cannot pay for

In general, CCSGs do not support research projects directly but are used to enhance the ongoing cancer research and to strengthen the existing research base according to the "Policies and Guidelines Relating to the Cancer Center Support Grant."

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Award range and average, in the agency's words

Range: $57,222 to $13,733,523 Average: $2,438,722

Quoted from the program's federal Assistance Listing. The notice of funding opportunity is the official source for each competition's rules.

Who usually wins

Colleges and universities received 69% of the money, nonprofits 28% and tribes less than 0.1%.

By state

Each state below has its own page for this program, with its recipients and yearly totals.

Award amounts are federal obligations reported to USAspending.gov for fiscal 2021 to 2025; see how our data works.