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PA-24-245: PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)

Closed Closed September 5, 2025 Opportunity PA-24-245

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants to small businesses. Applications closed on September 5, 2025.

From the official notice on Grants.gov, last changed April 1, 2025. Checked November 7, 2026.

About this NIH notice

The title gives no activity code; these are the codes of the projects NIH funded under it.

Projects funded under PA-24-245 were run by National Cancer Institute (NCI, 126 projects), National Institute of General Medical Sciences (NIGMS, 99 projects), National Institute of Allergy and Infectious Diseases (NIAID, 98 projects) and National Heart Lung and Blood Institute (NHLBI, 78 projects), and 26 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PA-24-245 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PA-23-230July 12, 2023Closed April 5, 2024Closed
PA-22-176June 2, 2022Closed April 5, 2023Closed
PA-21-259July 8, 2021Closed April 5, 2022Closed

Key dates

PostedJuly 3, 2024
DeadlineSeptember 5, 2025
Archived by Grants.govOctober 5, 2025

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

More grants for small businesses.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO), issued by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC), and the Food and Drug Administration (FDA), invites eligible United States small businesses to submit Small Business Innovation Research (SBIR) grant applications. United States small businesses that have the research capabilities and technological expertise to contribute to the R and D mission(s) of the NIH, CDC, and FDA awarding components identified in this NOFO are encouraged to submit SBIR grant applications in response to identified topics (see SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, and FDA).This Parent Funding Opportunity Announcement does not accept clinical trials.

Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services.

Funded under PA-24-245 so far

NIH funded 799 projects under PA-24-245 in fiscal 2025 to 2026, at 667 institutions. The median yearly award was $421,545.

Most projects: Mucommune, LLC (North Carolina), 8, Biotherapeutics, Inc. (Virginia), 6, Vivid Bioinnovations, PBC (California), 6, Innovative Design Labs, Inc. (Minnesota), 5, Panluminate Inc. (Connecticut), 5.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PA-24-245 still open?

No. It closed on September 5, 2025.

Who can apply for PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)?

Closed September 5, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PA-24-245?

NIH RePORTER lists 799 projects funded under PA-24-245 in fiscal 2025 to 2026, at 667 institutions. The most were at Mucommune, LLC, Biotherapeutics, Inc., Vivid Bioinnovations, PBC.

Who has won Environmental Health grants before?

The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.

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