PAR-24-264: High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants to nonprofits and colleges and universities. Applications closed on July 16, 2026.
From the official notice on Grants.gov, last changed July 15, 2026. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeS10
- Clinical trialsNot allowed
- Funded byOD
- Median yearly award$1.5 million
- Typical project length1 year
- S10, Shared Instrumentation Grant. Expensive research instruments shared by several NIH-funded investigators. Other open S10 notices.
Projects funded under PAR-24-264 were run by NIH Office of the Director (OD, 44 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-24-264 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-22-079 | January 7, 2022 | Closed June 3, 2024 | Closed |
| PAR-21-126 | February 8, 2021 | Closed June 15, 2021 | Closed |
Key dates
| Posted | October 29, 2024 |
|---|---|
| Deadline | July 16, 2026 |
| Archived by Grants.gov | August 15, 2026 |
Who can apply
This opportunity was open to nonprofits and colleges and universities.
- Public and State controlled institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Most of the money in the 3 programs behind this notice (80% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $750,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, nuclear magnetic resonance spectrometers, X-ray diffractometers, mass spectrometers, high throughput robotic screening systems, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.
Funded under PAR-24-264 so far
NIH funded 44 projects under PAR-24-264 in fiscal 2026, at 36 institutions. The median yearly award was $1.5 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Orbitrap Ascend Tribrid Mass Spectrometer System for Advancing Proteomics Research in Southeastern Wisconsin | Medical College of Wisconsin | 2026 | $1.5 million |
| Cryo-soft X-ray microscopy at NYSBC | New York Structural Biology Center | 2026 | $2.0 million |
| NovaSeq X Plus Sequencing System | University of Southern California | 2026 | $1.4 million |
| MINFLUX 3D Microscope | Texas A&m University Health Science Ctr | 2026 | $1.6 million |
| LUMICKS C-Trap Edge 350 | Utah State Higher Education System--University of Utah | 2026 | $1.1 million |
| Terra-X Upgrade for Siemens Whole Body 7T Terra MRI System | University of Pennsylvania | 2026 | $1.3 million |
| MinFlux super-resolution microscope | Johns Hopkins University | 2026 | $1.8 million |
| PowerEdge XE9680, a NVIDIA H200-powered AI Server | University of Miami School of Medicine | 2026 | $762,427 |
Who has won Biomedical Research and Research Training grants before
From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 186 | $290 million |
| Regents of the University of Michigan | Michigan | 226 | $268 million |
| University of California, San Diego | California | 198 | $264 million |
| Yale Univ | Connecticut | 195 | $250 million |
| University of Wisconsin System | Wisconsin | 169 | $241 million |
Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before
From fiscal 2021 to 2025, Discovery and Applied Research for Technological Innovations to Improve Human Health (93.286) awarded $1.8 billion across 1,983 grant awards, an average of $886,380 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The General Hospital Corporation | Massachusetts | 75 | $83.5 million |
| The Johns Hopkins University | Maryland | 68 | $83.5 million |
| The Leland Stanford Junior University | California | 64 | $53.0 million |
| Brigham & Womens Hospital Inc | Massachusetts | 41 | $49.5 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 44 | $48.3 million |
Who has won Research Infrastructure Programs grants before
From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of California, Davis | California | 27 | $102 million |
| Oregon Health & Science University | Oregon | 18 | $92.1 million |
| University of Washington | Washington | 7 | $79.5 million |
| Emory University | Georgia | 14 | $78.3 million |
| The Administrators of Tulane Educational Fund | Louisiana | 10 | $68.0 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-24-264 still open?
No. It closed on July 16, 2026.
Who can apply for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?
Closed July 16, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under PAR-24-264?
NIH RePORTER lists 44 projects funded under PAR-24-264 in fiscal 2026, at 36 institutions. The most were at New York Structural Biology Center, University of Minnesota, Johns Hopkins University.
Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before?
The largest recipients over five fiscal years were The General Hospital Corporation, The Johns Hopkins University, The Leland Stanford Junior University. The program made 1,983 awards worth $1.8 billion in that time.
Similar open grants
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
- Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
- Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
- Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
- Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)