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PAR-24-264: High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)

Closed Closed July 16, 2026 Opportunity PAR-24-264

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants to nonprofits and colleges and universities. Applications closed on July 16, 2026.

From the official notice on Grants.gov, last changed July 15, 2026. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-24-264 were run by NIH Office of the Director (OD, 44 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-24-264 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-22-079January 7, 2022Closed June 3, 2024Closed
PAR-21-126February 8, 2021Closed June 15, 2021Closed

Key dates

PostedOctober 29, 2024
DeadlineJuly 16, 2026
Archived by Grants.govAugust 15, 2026

Who can apply

This opportunity was open to nonprofits and colleges and universities.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities.

Is this a realistic fit?

What the grant funds

The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $750,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, nuclear magnetic resonance spectrometers, X-ray diffractometers, mass spectrometers, high throughput robotic screening systems, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.

Category: Health.

Funded under PAR-24-264 so far

NIH funded 44 projects under PAR-24-264 in fiscal 2026, at 36 institutions. The median yearly award was $1.5 million.

Most projects: New York Structural Biology Center (New York), 3, University of Minnesota (Minnesota), 3, Johns Hopkins University (Maryland), 2, Case Western Reserve University (Ohio), 2, University of California Los Angeles (California), 2.

Recently funded projects
ProjectInstitutionFiscal yearAward
Orbitrap Ascend Tribrid Mass Spectrometer System for Advancing Proteomics Research in Southeastern Wisconsin S10Medical College of Wisconsin2026$1.5 million
Cryo-soft X-ray microscopy at NYSBC S10New York Structural Biology Center2026$2.0 million
NovaSeq X Plus Sequencing System S10University of Southern California2026$1.4 million
MINFLUX 3D Microscope S10Texas A&m University Health Science Ctr2026$1.6 million
LUMICKS C-Trap Edge 350 S10Utah State Higher Education System--University of Utah2026$1.1 million
Terra-X Upgrade for Siemens Whole Body 7T Terra MRI System S10University of Pennsylvania2026$1.3 million
MinFlux super-resolution microscope S10Johns Hopkins University2026$1.8 million
PowerEdge XE9680, a NVIDIA H200-powered AI Server S10University of Miami School of Medicine2026$762,427

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before

From fiscal 2021 to 2025, Discovery and Applied Research for Technological Innovations to Improve Human Health (93.286) awarded $1.8 billion across 1,983 grant awards, an average of $886,380 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts75$83.5 million
The Johns Hopkins UniversityMaryland68$83.5 million
The Leland Stanford Junior UniversityCalifornia64$53.0 million
Brigham & Womens Hospital IncMassachusetts41$49.5 million
The Trustees of the University of PennsylvaniaPennsylvania44$48.3 million

Top states: Massachusetts ($277 million), California ($264 million), New York ($165 million), Maryland ($111 million), Pennsylvania ($94.9 million).

Who has won Research Infrastructure Programs grants before

From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia27$102 million
Oregon Health & Science UniversityOregon18$92.1 million
University of WashingtonWashington7$79.5 million
Emory UniversityGeorgia14$78.3 million
The Administrators of Tulane Educational FundLouisiana10$68.0 million

Top states: California ($183 million), Texas ($127 million), Oregon ($111 million), Massachusetts ($90.4 million), Washington ($87.3 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-24-264 still open?

No. It closed on July 16, 2026.

Who can apply for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?

Closed July 16, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-24-264?

NIH RePORTER lists 44 projects funded under PAR-24-264 in fiscal 2026, at 36 institutions. The most were at New York Structural Biology Center, University of Minnesota, Johns Hopkins University.

Who has won Discovery and Applied Research for Technological Innovations to Improve Human Health grants before?

The largest recipients over five fiscal years were The General Hospital Corporation, The Johns Hopkins University, The Leland Stanford Junior University. The program made 1,983 awards worth $1.8 billion in that time.

Similar open grants