PAR-21-126: High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants of up to $2.0 million to nonprofits and colleges and universities. It expected to make about 25 awards worth $30.0 million in total. Applications closed on June 15, 2021.
From the official notice on Grants.gov, last changed May 27, 2021. Checked November 7, 2026.
- Award ceiling$2.0 million
- Total funding$30.0 million
- Expected awards25
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeS10
- Clinical trialsNot allowed
- Funded byOD
- Median yearly award$1.2 million
- Typical project length1 year
- S10, Shared Instrumentation Grant. Expensive research instruments shared by several NIH-funded investigators. Other open S10 notices.
Projects funded under PAR-21-126 were run by NIH Office of the Director (OD, 46 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-21-126 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-24-264 | October 29, 2024 | Closed July 16, 2026 | Closed |
| PAR-22-079 | January 7, 2022 | Closed June 3, 2024 | Closed |
Key dates
| Posted | February 8, 2021 |
|---|---|
| Deadline | June 15, 2021 |
| Archived by Grants.gov | July 15, 2021 |
Who can apply
This opportunity was open to nonprofits and colleges and universities.
- Public and State controlled institutions of higher education
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $1.2 million; it allows up to $2.0 million per award.
- Most of the money in the 2 programs behind this notice (80% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The High-End Instrumentation (HEI) Grant program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $600,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, biomedical imagers, high throughput robotic screening systems, X-ray diffractometers, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, and cell sorters.
Funded under PAR-21-126 so far
NIH funded 46 projects under PAR-21-126 in fiscal 2022 to 2023, at 39 institutions. The median yearly award was $1.2 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| High-throughput Full Spectrum Cell Sorter | University of California, San Francisco | 2023 | $752,359 |
| EIGER2 S 16M Detector | University of California Berkeley | 2022 | $1.8 million |
| 600 MHz NMR Spectrometer and CPMAS CryoProbe | University of California Riverside | 2022 | $2.0 million |
| Console Replacement and Upgrade of 9.4 Tesla Animal Instrument | University of Minnesota | 2022 | $1.3 million |
| 7T Cryogen-Free Preclinical MRI for small animals to study infectious diseases in BSL-3 containment | Johns Hopkins University | 2022 | $1.7 million |
| Acquisition of a Focused Ion Beam Scanning Electron Microscope with cryo-stage | Vanderbilt University | 2022 | $1.6 million |
| High-Throughput DNA Sequencer | Tufts University Boston | 2022 | $804,465 |
| ThermoFisher Scientific Orbitrap Eclipse with ETD and UVPD | University of Washington | 2022 | $1.2 million |
Who has won Biomedical Research and Research Training grants before
From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 186 | $290 million |
| Regents of the University of Michigan | Michigan | 226 | $268 million |
| University of California, San Diego | California | 198 | $264 million |
| Yale Univ | Connecticut | 195 | $250 million |
| University of Wisconsin System | Wisconsin | 169 | $241 million |
Who has won Research Infrastructure Programs grants before
From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| University of California, Davis | California | 27 | $102 million |
| Oregon Health & Science University | Oregon | 18 | $92.1 million |
| University of Washington | Washington | 7 | $79.5 million |
| Emory University | Georgia | 14 | $78.3 million |
| The Administrators of Tulane Educational Fund | Louisiana | 10 | $68.0 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-21-126 still open?
No. It closed on June 15, 2021.
Who can apply for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)?
Closed June 15, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $2.0 million each. About $30.0 million in total across about 25 awards.
Who has been funded under PAR-21-126?
NIH RePORTER lists 46 projects funded under PAR-21-126 in fiscal 2022 to 2023, at 39 institutions. The most were at H. Lee Moffitt Cancer Ctr & Res Inst, University of California Berkeley, Vanderbilt University.
Who has won Research Infrastructure Programs grants before?
The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.
Similar open grants
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
- Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)
- Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)
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- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
- Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)