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PAR-22-080: Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Closed Closed June 3, 2024 Opportunity PAR-22-080

This grant is closed. A newer notice from the same program is open now: Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (PAR-27-022). Status: Due dates in the notice, expires July 1, 2028. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits and colleges and universities. Applications closed on June 3, 2024.

From the official notice on Grants.gov, last changed January 7, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-080 were run by NIH Office of the Director (OD, 196 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-080 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-27-022June 25, 2026Due dates in the notice, expires July 1, 2028Open
PAR-24-265October 29, 2024Closed July 16, 2026Closed
PAR-21-127February 8, 2021Closed June 15, 2021Closed

Key dates

PostedJanuary 7, 2022
DeadlineJune 3, 2024
Archived by Grants.govJuly 9, 2024

Who can apply

This opportunity was open to nonprofits and colleges and universities.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities.

Is this a realistic fit?

What the grant funds

The Shared Instrument Grant (SIG) Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-priced, specialized, commercially available instruments or integrated instrumentation system. The minimum award is $50,000. There is no maximum price limit for the instrument; however, the maximum award is $600,000. Instruments supported include, but are not limited to: X-ray diffractometers, mass spectrometers, nuclear magnetic resonance spectrometers, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.

Category: Health.

Funded under PAR-22-080 so far

NIH funded 196 projects under PAR-22-080 in fiscal 2023 to 2025, at 97 institutions. The median yearly award was $551,577.

Most projects: Massachusetts General Hospital (Massachusetts), 11, Johns Hopkins University (Maryland), 8, Vanderbilt University Medical Center (Tennessee), 6, University of Colorado Denver (Colorado), 6, University of Pennsylvania (Pennsylvania), 5.

Recently funded projects
ProjectInstitutionFiscal yearAward
Digital multi-isotope autoradiography system S10Massachusetts General Hospital2025$255,500
Waters Desorption Electrospray (DESI) XS TQ Absolute imaging mass spectrometry system S10University of Texas Med BR Galveston2025$593,598
The BD FACSDiscover S8 Cell Sorter for Flow Cytometric Sorting S10Pennsylvania State Univ Hershey Med Ctr2025$631,365
"The Evident FV-4000 Confocal Microscope" S10Johns Hopkins University2025$740,044
High parameter fluorescence activated cell sorter S10Versiti Blood Health, Inc.2025$679,925
Laser Ablation System for Ultrafast Elemental Mapping of Clinical and Preclinical Biospecimens S10Boston University Medical Campus2025$316,012
Olympus FV4000-MPE Multiphoton Microscope for Intravital Imaging S10University of Pennsylvania2025$749,993
CAGT Shared Instrumentation Grant: IncuCyte SX5 Imaging System S10Baylor College of Medicine2025$248,962

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Who has won Research Infrastructure Programs grants before

From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia27$102 million
Oregon Health & Science UniversityOregon18$92.1 million
University of WashingtonWashington7$79.5 million
Emory UniversityGeorgia14$78.3 million
The Administrators of Tulane Educational FundLouisiana10$68.0 million

Top states: California ($183 million), Texas ($127 million), Oregon ($111 million), Massachusetts ($90.4 million), Washington ($87.3 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-27-022, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-080 still open?

No. It closed on June 3, 2024. A newer notice is open: PAR-27-022, due dates in the notice, expires July 1, 2028.

Who can apply for Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)?

Closed June 3, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-22-080?

NIH RePORTER lists 196 projects funded under PAR-22-080 in fiscal 2023 to 2025, at 97 institutions. The most were at Massachusetts General Hospital, Johns Hopkins University, Vanderbilt University Medical Center.

Who has won Research Infrastructure Programs grants before?

The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.

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