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Grants / Department of Health and Human Services / National Institutes of Health

PAR-23-237: Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)

Closed Closed January 25, 2026 Opportunity PAR-23-237

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 25, 2026.

From the official notice on Grants.gov, last changed August 31, 2023. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-23-237 were run by National Human Genome Research Institute (NHGRI, 4 projects), National Cancer Institute (NCI, 4 projects), National Institute of Biomedical Imaging and Bioengineering (NIBIB, 3 projects) and National Institute of Environmental Health Sciences (NIEHS, 2 projects), and 4 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-23-237 in the NIH Guide.

Key dates

PostedAugust 30, 2023
DeadlineJanuary 25, 2026
Archived by Grants.govMarch 2, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The purpose of this Notice of Funding Opportunity (NOFO) is to support established biomedical data resources, that have demonstrated impact and have potential for continued benefit to the mission of one or more of the NIH Institutes and Centers participating in this announcement. Each application must: (a) deliver scientific impact to the communities served; (b) employ and promote good data management practices (as outlined by the FAIR Data Principles including adherence to the NIH desirable characteristics of repositories) and efficient operations for quality and services; (c) engage with the user community and continuously address their needs; and (d) support a process for data life-cycle analysis, long-term preservation, and trustworthy governance. The evaluation of the repositories will be based on their usage, utility, impact, quality of data and services, and efficiency of operations, community needs and engagement, trustworthiness of stewardship, and governance.

Category: Education, Environment, Health.

Funded under PAR-23-237 so far

NIH funded 17 projects under PAR-23-237 in fiscal 2024 to 2026, at 16 institutions. The median yearly award was $1.2 million.

Most projects: University of California, San Diego (California), 2, University of Cambridge, 1, Sloan-Kettering Inst Can Research (New York), 1, Georgetown University (District of Columbia), 1, Icahn School of Medicine at Mount Sinai (New York), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
The Nomenclature of Human and Vertebrate Genes U24University of Cambridge2026$501,093
Expanding OncoKB, a scalable and reliable precision oncology knowledgebase. U24Sloan-Kettering Inst Can Research2026$736,625
UniProt: AI-Driven Scaling of Protein Knowledge for Biomedical Research U24Georgetown University2026$875,383
ENvironmental Data: AI-Ready (ENDAR) Data Repository U24Icahn School of Medicine at Mount Sinai2026$1.7 million
Metabolomics Workbench - National Metabolomics Data Repository U24University of California, San Diego2026$1.4 million
Alliance Central: A platform for sustainable development of next generation genome knowledgebases U24California Institute of Technology2026$4.9 million
The Molecular Signatures Database: A knowledgebase for gene set based analysis of genomic data U24University of California, San Diego2026$654,616
Medical Imaging and Data Resource Center (MIDRC) – Expansion to Theranostics U24University of Chicago2026$1.0 million

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-23-237 still open?

No. It closed on January 25, 2026.

Who can apply for Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)?

Closed January 25, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-23-237?

NIH RePORTER lists 17 projects funded under PAR-23-237 in fiscal 2024 to 2026, at 16 institutions. The most were at University of California, San Diego, University of Cambridge, Sloan-Kettering Inst Can Research.

Who has won Environmental Health grants before?

The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.

Similar open grants