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PAR-22-081: Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)

Closed Closed June 3, 2024 Opportunity PAR-22-081

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits and colleges and universities. Applications closed on June 3, 2024.

From the official notice on Grants.gov, last changed January 7, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-081 were run by NIH Office of the Director (OD, 14 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-081 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-24-326October 29, 2024Closed July 16, 2026Closed
PAR-21-125February 8, 2021Closed June 15, 2021Closed

Key dates

PostedJanuary 7, 2022
DeadlineJune 3, 2024
Archived by Grants.govJuly 9, 2024

Who can apply

This opportunity was open to nonprofits and colleges and universities.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for nonprofits, colleges and universities.

Is this a realistic fit?

What the grant funds

The Basic Instrumentation Grant (BIG) Program encourages applications from groups of NIH-supported investigators to purchase a single high-priced, specialized, commercially available instrument or an integrated instrumentation system. The BIG Program is limited to institutions that have not received S10 instrumentation funding of $250,001 or greater in any of the preceding 3 Federal fiscal years (FY). Use the following to determine applicable funding periods: for application due date of June 1, 2022, consider S10 funding in FYs 2019-2021; for application due date of June 1, 2023, consider S10 funding in FYs 2020-2022; for application due date of June 3, 2024, consider S10 funding in FYs 2021-2023. The minimum award is $25,000. There is no maximum price limit for the instrument; however, the maximum award is $250,000. Instruments supported include, but are not limited to, basic cell sorters, confocal microscopes, ultramicrotomes, gel imagers, or computer systems.

Category: Health.

Funded under PAR-22-081 so far

NIH funded 14 projects under PAR-22-081 in fiscal 2023 to 2025, at 13 institutions. The median yearly award was $249,252.

Most projects: University of Notre Dame (Indiana), 2, West Virginia University (West Virginia), 1, Boston Medical Center (Massachusetts), 1, Providence College (Rhode Island), 1, Auburn University at Auburn (Alabama), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
Metabolic Monitoring System for Animal Models & Imaging Facility. S10West Virginia University2025$349,990
Utilization of BioDot Omnia Automated Liquid Dispensing/Handling System to Enhance the Efficiency and Accuracy of High Throughput Biological Assays S10Boston Medical Center2025$248,757
Spinning Disk Confocal Microscope System S10Providence College2025$348,584
A shared Agilent 6546 LC-QTOF for biomedical research S10Auburn University at Auburn2025$348,724
Beckman Optima A/I Analytical Ultracentrifuge (AUC) S10University of Notre Dame2025$350,000
Multipurpose Upright Optical Microscope for Imaging Core S10Virginia Commonwealth University2025$249,747
ONI NanoImager S10Children's Hospital of Los Angeles2025$333,128
Enhancing Imaging Efficiency through Automated Slide Scanning Image Acquisition S10MC Laughlin Research Institute2025$170,675

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Who has won Research Infrastructure Programs grants before

From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia27$102 million
Oregon Health & Science UniversityOregon18$92.1 million
University of WashingtonWashington7$79.5 million
Emory UniversityGeorgia14$78.3 million
The Administrators of Tulane Educational FundLouisiana10$68.0 million

Top states: California ($183 million), Texas ($127 million), Oregon ($111 million), Massachusetts ($90.4 million), Washington ($87.3 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-081 still open?

No. It closed on June 3, 2024.

Who can apply for Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)?

Closed June 3, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-22-081?

NIH RePORTER lists 14 projects funded under PAR-22-081 in fiscal 2023 to 2025, at 13 institutions. The most were at University of Notre Dame, West Virginia University, Boston Medical Center.

Who has won Research Infrastructure Programs grants before?

The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.

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