NIH R42 funding opportunities: Small Business Technology Transfer (STTR) Phase II
1 NIH notice for R42 (Small Business Technology Transfer (STTR) Phase II) is open and 2 forecast. Full development of an STTR project after Phase I.
- Open notices1
- Forecast2
- Projects funded under them1,882
Open NIH R42 notices
Forecast R42 notices
- Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)
Forecast - Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)
Forecast
Institutes that fund R42 projects under these notices
| Institute or center | Projects |
|---|---|
| National Cancer Institute (NCI) | 273 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 251 |
| National Heart Lung and Blood Institute (NHLBI) | 209 |
| National Institute of General Medical Sciences (NIGMS) | 127 |
| National Institute on Aging (NIA) | 126 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 122 |
| National Institute of Neurological Disorders and Stroke (NINDS) | 93 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 92 |
| National Institute of Mental Health (NIMH) | 73 |
| National Institute on Drug Abuse (NIDA) | 71 |
Closed R42 notices
- RFA-DA-25-047: Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)
- PAR-24-044: NINDS Exploratory Clinical Trials for Small Business (R41/R42 Clinical Trial Required)
- RFA-MD-24-007: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
- PAR-24-133: Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed)
- PAR-24-134: Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Required)
- PAS-22-197: Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)
- PA-24-247: PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
- PA-24-248: PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
- RFA-NS-23-007: HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
- PAR-24-157: Addressing Health Inequities in Clinical Diagnostics (R41/R42 Clinical Trials Not Allowed)
- RFA-DA-26-019: Addressing Challenges in Detecting New Drugs: Instrumentation for Alternative Analytical Methods (R41/R42 - Clinical Trials Optional)
- RFA-DA-24-038: Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)
- PAR-21-226: Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)
- RFA-DA-25-049: Solutions to enable diagnosis and treatment of adverse health consequences of non-disordered drug use (R41/R42 - Clinical Trial Optional)
- PAR-24-262: STTR Solutions to Enable Population Genomic Screening (R41/R42 Clinical Trial Optional)
- PA-21-345: Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)
- RFA-CA-24-023: Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)
- RFA-DA-25-053: Harnessing Artificial Intelligence and Polypharmacology to Discover Pharmacotherapeutics for Substance Use Disorders (R41/R42 Clinical Trials Not Allowed)
- PAR-24-107: Solutions to Enable Regional Genomic Medicine eConsult Services (R41/R42 Clinical Trial Optional)
- RFA-AA-24-002: High-Throughput Screening (HTS) Platform for Discovery of Medications to Treat Alcohol Use Disorder (R41/R42 Clinical Trials Not Allowed)
- PA-23-231: PHS 2023-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
- PA-23-232: PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
- PA-23-233: PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
- RFA-DA-25-051: Tools for Decentralized Clinical Trials for Substance Use Disorder (R41/R42 Clinical Trials Optional)
- PAR-22-073: Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed)
- PAR-21-298: Multipurpose Prevention Technology: Novel Systemic Options for Young Adults (R41/R42 Clinical Trial Not Allowed)
- PAR-21-267: NINDS Exploratory Clinical Trials for Small Business (R41/R42 Clinical Trial Required)
- RFA-DA-24-017: Field-Deployable, Low-Cost Point-of-Need Approaches and Technologies to Lower the Barriers to Substance Use Disorders (SUD) Diagnosis and Treatment (R41/R42 Clinical Trial Optional)
- RFA-AG-24-043: NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)
- RFA-MD-23-002: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
- RFA-CA-23-035: Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)
- PA-22-178: PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
- PA-22-179: PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
- PA-22-176: PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
- RFA-AG-23-030: NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)
- RFA-DA-23-019: Novel Drug (DDT) and Medical Device Development Tools (MDDT) to Help Expedite Creation and Regulatory Approvals of New Therapies for Substance Use Disorders (SUD) (R41/R42 Clinical Trial Optional)
- RFA-DE-23-007: Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (R42 Fast-Track - Clinical Trial Not Allowed)
- RFA-CA-22-017: Small Business Transition Grant For Early Career Scientists (R42 Clinical Trial Not Allowed)
- PA-21-262: PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
- PA-21-261: PHS 2021-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required)
- RFA-MD-22-003: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
- RFA-DA-22-018: Advancing Validated Drug Targets for Substance Use Disorders (R41/R42 - Clinical Trial Not Allowed)
- RFA-ES-21-009: Innovative Approaches for Improving Environmental Health Literacy (R41/R42 Clinical Trial Not Allowed)
- RFA-AG-22-014: NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)
- RFA-DA-22-021: Leveraging Artificial Intelligence (AI) tools for Substance Use Disorders (SUD) drug discovery and development (R41/R42 - Clinical Trial Not Allowed)
- RFA-MD-21-005: Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
Questions people ask
What is an NIH R42?
R42 is NIH's activity code for the Small Business Technology Transfer (STTR) Phase II. Full development of an STTR project after Phase I. Each notice sets its own budget limit, project length and due dates.
How many NIH R42 funding opportunities are open?
1 notice is open on Grants.gov, and 2 more are forecast, as of the latest data.