RFA-AA-24-002: High-Throughput Screening (HTS) Platform for Discovery of Medications to Treat Alcohol Use Disorder (R41/R42 Clinical Trials Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants of up to $500,000 to small businesses. Applications closed on April 9, 2024.
From the official notice on Grants.gov, last changed December 21, 2023. Checked November 7, 2026.
- Award ceiling$500,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR41 / R42
- Clinical trialsNot allowed
- Funded byNIAAA
- Median yearly award$423,313
- Typical project length1 year
- R41, Small Business Technology Transfer (STTR) Phase I. A small business and a research institution test the feasibility of a technology together. Other open R41 notices.
- R42, Small Business Technology Transfer (STTR) Phase II. Full development of an STTR project after Phase I. Other open R42 notices.
Projects funded under RFA-AA-24-002 were run by National Institute on Alcohol Abuse and Alcoholism (NIAAA, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-AA-24-002 in the NIH Guide.
Key dates
| Posted | December 21, 2023 |
|---|---|
| Deadline | April 9, 2024 |
| Archived by Grants.gov | May 15, 2024 |
Who can apply
This opportunity was open to small businesses.
- Small businesses
Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $423,313; it allows up to $500,000 per award.
- Most of the program's money (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This Notice of Funding Opportunity (NOFO) supports Small Business Technology Transfer (STTR) applications from small business concerns (SBCs) in the development of a new, or optimization of an existing, in vivo and/or in vitro high-throughput screening (HTS) platform for use in identifying potential compounds for treating alcohol use disorder (AUD). Potential screening platform assays will consist of small vertebrate (excluding rodent) and invertebrate model organisms and human cell- and tissue-based models. The platform assays must be sensitive to different concentrations of alcohol, as well as treatment effects, such that any changes to the model can be measured accurately and reproducibly and can be used as outcome variables.
Funded under RFA-AA-24-002 so far
NIH funded 1 project under RFA-AA-24-002 in fiscal 2025, at 1 institution. The median yearly award was $423,313.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| AI-driven in vivo profiling in zebrafish: a platform for alcohol use disorder therapeutic discovery | Biosymetrics, Inc. | 2025 | $423,313 |
Who has won Alcohol Research Programs grants before
From fiscal 2021 to 2025, Alcohol Research Programs (93.273) awarded $2.2 billion across 2,255 grant awards, an average of $974,579 per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 75 | $86.5 million |
| University of North Carolina at Chapel Hill | North Carolina | 76 | $60.7 million |
| Trustees of Indiana University | Indiana | 47 | $54.8 million |
| University of California, San Diego | California | 47 | $54.5 million |
| The Medical University of South Carolina | South Carolina | 57 | $45.8 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-AA-24-002 still open?
No. It closed on April 9, 2024.
Who can apply for High-Throughput Screening (HTS) Platform for Discovery of Medications to Treat Alcohol Use Disorder (R41/R42 Clinical Trials Not Allowed)?
National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for High-Throughput Screening (HTS) Platform for Discovery of Medications to Treat Alcohol Use Disorder (R41/R42 Clinical Trials Not Allowed)?
Closed April 9, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each.
Who has been funded under RFA-AA-24-002?
NIH RePORTER lists 1 project funded under RFA-AA-24-002 in fiscal 2025, at 1 institution.
Who has won Alcohol Research Programs grants before?
The largest recipients over five fiscal years were Yale Univ, University of North Carolina at Chapel Hill, Trustees of Indiana University. The program made 2,255 awards worth $2.2 billion in that time.
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