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PAR-24-075: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Closed Closed May 23, 2025 Opportunity PAR-24-075

This grant is closed. A newer notice from the same program is open now: Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) (PAR-25-322). Status: Due dates in the notice, expires August 25, 2028. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 23, 2025.

From the official notice on Grants.gov, last changed May 15, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-24-075 were run by National Heart Lung and Blood Institute (NHLBI, 6 projects), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, 4 projects), National Institute of Dental and Craniofacial Research (NIDCR, 4 projects) and National Institute of Mental Health (NIMH, 3 projects), and 10 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-24-075 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-322August 25, 2025Due dates in the notice, expires August 25, 2028Open

Key dates

PostedDecember 22, 2023
DeadlineMay 23, 2025
Archived by Grants.govJune 22, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.

Category: Education, Food and Nutrition, Health, Income Security and Social Services.

Funded under PAR-24-075 so far

NIH funded 38 projects under PAR-24-075 in fiscal 2024 to 2026, at 32 institutions. The median yearly award was $674,725.

Most projects: Arizona State University-Tempe Campus (Arizona), 2, Northwestern University (Illinois), 2, Hugo W. Moser Res Inst Kennedy Krieger (Maryland), 2, Oregon Health & Science University (Oregon), 2, University of California, San Diego (California), 2.

Recently funded projects
ProjectInstitutionFiscal yearAward
Towards MRI-based detection and categorization of invasive high grade glioma subtypes R37Arizona State University-Tempe Campus2026$513,775
Cytokine-mediated tuning of neural circuits underlying avoidance behavior R01Northwestern University2026$708,139
Physical activity timing in relation to glycemic control for night workers versus day workers R01University of Illinois at Chicago2026$516,468
Role of human NK cells in the immune response to Coccidioides R56Northern California Institute/Res/Edu2026$712,977
Aligning Machine Learning Models with Clinician Knowledge for Understanding, Prediction, and Prevention of Suicide R01Wellesley College2026$707,584
Development and Validation of the Sibling Prosocial Relationship Questionnaire R01Case Western Reserve University2026$609,628
Cellular heterogeneity in mitochondrial calcium dynamics in heart failure R01Wake Forest University Health Sciences2026$492,014
Targeting Regulatory T cells for Factor VIII Tolerance R01Stanford University2026$758,254

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before

From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan273$345 million
The Trustees of the University of PennsylvaniaPennsylvania187$272 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania209$238 million
The Washington UniversityMissouri187$227 million
The Regents of the University of California, San FranciscoCalifornia176$208 million

Top states: California ($1.2 billion), Massachusetts ($932 million), New York ($798 million), Pennsylvania ($762 million), Texas ($482 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-25-322, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-24-075 still open?

No. It closed on May 23, 2025. A newer notice is open: PAR-25-322, due dates in the notice, expires August 25, 2028.

Who can apply for Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)?

Closed May 23, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-24-075?

NIH RePORTER lists 38 projects funded under PAR-24-075 in fiscal 2024 to 2026, at 32 institutions. The most were at Arizona State University-Tempe Campus, Northwestern University, Hugo W. Moser Res Inst Kennedy Krieger.

Who has won Human Genome Research grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.

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