Federal grants to Epicypher, Inc.
Epicypher, Inc. in Research Triangle Park, North Carolina received $47.3 million in federal grants from fiscal 2021 to 2025, across 27 awards. Its largest program was Biomedical Research and Research Training, with $14.4 million. In fiscal 2025 it was awarded $10.4 million.
From USAspending.gov award records, updated October 31, 2026.
- Grants, FY 2021 to 2025$47.3 million
- Awards27
- Awarded in FY 2025$10.4 million
- Largest award$3.0 million
By year
| Fiscal year | Awards | Amount |
|---|---|---|
| FY 2021 | 1 | $788,741 |
| FY 2022 | 14 | $11.9 million |
| FY 2023 | 13 | $12.6 million |
| FY 2024 | 10 | $11.6 million |
| FY 2025 | 9 | $10.4 million |
Programs that fund Epicypher, Inc.
| Program | Awards | Amount |
|---|---|---|
| Biomedical Research and Research Training | 7 | $14.4 million |
| Allergy and Infectious Diseases Research | 5 | $12.1 million |
| Human Genome Research | 6 | $8.2 million |
| Aging Research | 4 | $6.8 million |
| National Center for Advancing Translational Sciences | 1 | $2.1 million |
| Diabetes, Digestive, and Kidney Diseases Extramural Research | 1 | $2.0 million |
| Cancer Detection and Diagnosis Research | 2 | $1.5 million |
| Drug Use and Addiction Research Programs | 1 | $326,506 |
Awarding agencies
| Agency | Awards | Amount |
|---|---|---|
| Department of Health and Human Services | 27 | $47.3 million |
Largest awards
| Award | Program | First action | Amount |
|---|---|---|---|
| Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cells - project summary histone post-translational modifications (PTMS) play important roles in modulating chromatin structure and gene expression, and dysregulation of these marks is associated with immune and inflammat | Allergy and Infectious Diseases Research | August 18, 2022 | $3.0 million |
| Rapid and robust assay for measurement of in vivo activity of chromatin-interacting proteins - project summary the activity of chromatin-associating proteins (CAPS) is fundamental to regulation of gene expression. Elucidating cap activity is central to understanding the regulatory mechanisms that dr | Allergy and Infectious Diseases Research | July 19, 2023 | $3.0 million |
| Development of ultra-efficient antibodies for single cell mapping applications - project summary histone post-translational modifications (PTMS) are some of the most widely studied epigenomic factors, and alterations in histone ptm abundance / distribution have been implicated in numerous disease et | Allergy and Infectious Diseases Research | March 10, 2023 | $3.0 million |
| Multiomic genomic mapping with long read sequencing - project summary genomic mapping of histone post-translational modifications (PTMS), chromatin-associated proteins (CAPS), and dna methylation (DNAME) is a powerful approach for biomedical research and drug development. Current genomics assays (e. | Biomedical Research and Research Training | August 12, 2022 | $3.0 million |
| Ultrasensitive multiomic platform using epitope-targeted dna methylation mapping - candidate eligibility statement the goal of this diversity supplement application is to provide career development support for dr. Allison hickman, a bioinformatician who aspires to (and with support could perform) le | Human Genome Research | January 25, 2022 | $2.9 million |
| Novel recombinant sensors to study histone ubiquitin signaling - project summary monoubiquitination (UB) of histones is an important post-translational modification (PTM) that regulates multiple dna-related processes including dna replication, transcription, and repair. Aberrant regulation of histon | Biomedical Research and Research Training | May 29, 2023 | $2.5 million |
| Versatile platform for genome-wide r-loop mapping for aging and neurodegenerative disease research - project summary r-loops are triple-stranded nucleic acid structures consisting of a dna: rna hybrid and a displaced single dna strand. R-loops are generally transient in nature, but persistence of sta | Aging Research | September 23, 2024 | $2.5 million |
| Biochemical and genomic tools to study histone adp ribosylation signaling - project summary histone adp-ribosylation (ADPR) is a complex post-translational modification (PTM) with strong disease associations. Adpr occurs on all five histone proteins in diverse states (e.g., mono-, di-, tri-, poly-ad | Biomedical Research and Research Training | February 6, 2024 | $2.5 million |
| Versatile genomics platform for unbiased analysis of chromatin-associated rnas and nascent transcripts - summary aging and neurodegenerative diseases, such as alzheimer’s disease and related dementias (ad/adrd), are associated with alterations in nuclear structure, chromatin dysregulation, genome in | Aging Research | August 12, 2024 | $2.5 million |
| A molecular toolbox to accelerate drug development for histone lysine methylation regulators - project summary nucleosomes (NUCS) are the repeating unit of chromatin structure and are decorated with diverse post- translational modifications (PTMS) to regulate gene expression. The enzymes that add an | National Center for Advancing Translational Sciences | April 29, 2022 | $2.1 million |
Questions people ask
How much federal grant money does Epicypher, Inc. get?
$47.3 million in 27 grant awards from fiscal 2021 to 2025, as obligations reported to USAspending.gov.
Which agency gives Epicypher, Inc. the most?
The Department of Health and Human Services, with $47.3 million in 27 awards.
What is Epicypher, Inc.'s largest federal grant?
$3.0 million under Allergy and Infectious Diseases Research, with its first action in the period on August 18, 2022. That counts only the money obligated in fiscal 2021 to 2025.
Which federal programs fund Epicypher, Inc.?
Its largest are Biomedical Research and Research Training, Allergy and Infectious Diseases Research and Human Genome Research.
Other grant recipients in Research Triangle Park
- Research Triangle Institute
- T3D Therapeutics, Inc.
- Redbud Labs, Inc.
- Altis Biosystems, Inc.
- Dignify Therapeutics, LLC
- Zymtronix Catalytic Systems, Inc.
- 21MEDTECH LLC
- North Carolina Biotechnology Center
Largest federal grant recipients in North Carolina · Federal grants in North Carolina