| 1 | North Carolina Department of Health & Human Services · Raleigh | State and local governments | 660 | $108 billion |
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| 2 | North Carolina Department of Public Instruction · Raleigh | State and local governments | 118 | $13 billion |
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| 3 | Transportation North Carolina Department · Raleigh | State and local governments | 4,732 | $8.3 billion |
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| 4 | North Carolina Department of Public Safety · Raleigh | State and local governments | 287 | $4.0 billion |
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| 5 | Duke University · Durham | Colleges and universities | 2,696 | $3.7 billion |
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| 6 | University of North Carolina at Chapel Hill · Chapel Hill | Colleges and universities | 2,767 | $3.3 billion |
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| 7 | North Carolina Department of Environmental Quality · Raleigh | State and local governments | 250 | $2.6 billion |
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| 8 | Family Health International · Durham | Nonprofits | 162 | $2.4 billion |
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| 9 | North Carolina Department of Public Instruction · Raleigh | State and local governments | 26 | $2.4 billion |
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| 10 | Department of Commerce North Carolina · Raleigh | State and local governments | 28 | $1.7 billion |
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| 11 | Research Triangle Institute · Research Triangle Park | Nonprofits | 346 | $1.6 billion |
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| 12 | Department of Information Technology · Raleigh | State and local governments | 3 | $1.6 billion |
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| 13 | North Carolina State University · Raleigh | Colleges and universities | 1,718 | $1.3 billion |
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| 14 | City of Charlotte · Charlotte | State and local governments | 136 | $1.1 billion |
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| 15 | Wake Forest University Health Sciences · Winston Salem | Colleges and universities | 559 | $790 million |
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| 16 | North Carolina Agricultural and Technical State University · Greensboro | Colleges and universities | 339 | $568 million |
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| 17 | North Carolina Department of Commerce · Raleigh | State and local governments | 58 | $553 million |
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| 18 | North Carolina Department of Natural and Cultural Resources · Raleigh | State and local governments | 71 | $523 million |
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| 19 | North Carolina Wildlife Resources Commission · Raleigh | State and local governments | 147 | $499 million |
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| 20 | Governors Office · Raleigh | State and local governments | 7 | $492 million |
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| 21 | Division of Employment Security · Raleigh | State and local governments | 24 | $447 million |
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| 22 | Grow Early Learning Corp. · Raleigh | Nonprofits | 7 | $356 million |
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| 23 | North Carolina Department of Transportation · Raleigh | State and local governments | 51 | $356 million |
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| 24 | Albemarle U.S., Inc. · Charlotte | Businesses | 3 | $307 million |
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| 25 | Telamon Corporation · Raleigh | Nonprofits | 69 | $300 million |
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| 26 | Asheville, City of · Asheville | State and local governments | 54 | $279 million |
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| 27 | North Carolina Central University · Durham | Colleges and universities | 108 | $257 million |
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| 28 | University of North Carolina at Charlotte · Charlotte | Colleges and universities | 320 | $252 million |
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| 29 | Raleigh-Durham Airport Authority · Raleigh | State and local governments | 21 | $244 million |
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| 30 | Volvo Technology of America, LLC · Greensboro | Businesses | 2 | $225 million |
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| 31 | East Carolina University · Greenville | Colleges and universities | 216 | $211 million |
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| 32 | North Carolina Department of Agriculture & Consumer Services · Raleigh | State and local governments | 259 | $207 million |
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| 33 | Cirba Solutions, LLC · Charlotte | Businesses | 3 | $205 million |
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| 34 | Eastern Band of Cherokee Indians · Cherokee | Tribal governments and organizations | 257 | $200 million |
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| 35 | North Carolina Housing Finance Agency · Raleigh | State and local governments | 13 | $195 million |
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| 36 | University of North Carolina at Greensboro · Greensboro | Colleges and universities | 149 | $189 million |
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| 37 | Winston-Salem State University · Winston Salem | Colleges and universities | 56 | $174 million |
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| 38 | City of Raleigh · Raleigh | State and local governments | 51 | $170 million |
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| 39 | Fayetteville State University · Fayetteville | Colleges and universities | 74 | $169 million |
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| 40 | Aviation Division · Raleigh | State and local governments | 32 | $149 million |
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| 41 | Appalachian State University · Boone | Colleges and universities | 81 | $142 million |
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| 42 | Lumbee Land Development, Inc · Pembroke | Tribal governments and organizations | 21 | $133 million |
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| 43 | North Carolina Community College System Office · Raleigh | State and local governments | 10 | $125 million |
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| 44 | Department of Military & Veterans Affairs North Carolina · Raleigh | State and local governments | 11 | $123 million |
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| 45 | City of Greensboro · Greensboro | State and local governments | 79 | $120 million |
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| 46 | Housing Authority of the City of Durham · Durham | State and local governments | 88 | $115 million |
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| 47 | Mecklenburg County · Charlotte | State and local governments | 71 | $112 million |
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| 48 | Intrahealth International, Inc. · Chapel Hill | Nonprofits | 7 | $109 million |
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| 49 | Rho Federal Systems Division Inc · Durham | Small businesses | 8 | $109 million |
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| 50 | Generationed · Greensboro | Nonprofits | 7 | $108 million |
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| 51 | Samaritans Purse · Boone | Nonprofits | 11 | $99.8 million |
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| 52 | Greater Asheville Regional Airport Authority · Fletcher | State and local governments | 20 | $98.1 million |
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| 53 | City of Durham · Durham | State and local governments | 32 | $89.5 million |
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| 54 | North Carolina Department of Transportation · Raleigh | State and local governments | 12 | $88.6 million |
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| 55 | Elizabeth City State University · Elizabeth City | Colleges and universities | 53 | $80.4 million |
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| 56 | The Trust for Tomorrow · Fairfield | Nonprofits | 44 | $78.8 million |
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| 57 | University of North Carolina at Wilmington · Wilmington | Colleges and universities | 100 | $78.7 million |
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| 58 | Economic Improvement Council, Inc. · Edenton | Nonprofits | 13 | $73.1 million |
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| 59 | New Hanover County Airport Authority · Wilmington | State and local governments | 17 | $70.6 million |
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| 60 | Families & Communities Rising, Inc. · Durham | Nonprofits | 7 | $70.2 million |
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| 61 | Wake Technical Community College · Raleigh | State and local governments | 13 | $70.1 million |
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| 62 | Tri County Community Health Council, Inc · Dunn | Other | 9 | $69.9 million |
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| 63 | Exela Pharma Sciences LLC · Lenoir | Small businesses | 2 | $68.7 million |
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| 64 | Gaston Family Health Services, Inc. · Gastonia | Other | 15 | $66.7 million |
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| 65 | Goshen Medical Center, Inc · Faison | Other | 12 | $66.7 million |
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| 66 | Central Piedmont Community College · Charlotte | Colleges and universities | 7 | $66.6 million |
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| 67 | Southeastern Community Action Partnership, Inc. · Lumberton | Nonprofits | 5 | $66.6 million |
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| 68 | Town of Chapel Hill · Chapel Hill | State and local governments | 43 | $64.8 million |
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| 69 | Wake Forest University · Winston Salem | Colleges and universities | 86 | $62.5 million |
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| 70 | Li Industries, Inc. · Pineville | Businesses | 4 | $62.1 million |
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| 71 | Piedmont Triad Airport Authority · Greensboro | State and local governments | 12 | $61.7 million |
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| 72 | Housing Authority of the City of Winston-Salem · Winston Salem | State and local governments | 113 | $61.6 million |
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| 73 | Piedmont Health Services Inc · Chapel Hill | Nonprofits | 10 | $61.0 million |
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| 74 | Greene County Health Care, Incorporated · Snow Hill | Other | 8 | $60.9 million |
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| 75 | Western Carolina University · Cullowhee | Colleges and universities | 40 | $58.7 million |
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| 76 | Wayne Action Group for Economic Solvency, Inc. · Goldsboro | Nonprofits | 12 | $58.7 million |
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| 77 | Johnson C. Smith University, Incorporated · Charlotte | Colleges and universities | 29 | $58.2 million |
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| 78 | Housing Authority of the City of Goldsboro, N.C · Goldsboro | State and local governments | 49 | $58.2 million |
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| 79 | The University of North Carolina at Pembroke · Pembroke | Colleges and universities | 46 | $57.9 million |
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| 80 | Action Pathways Inc · Fayetteville | Nonprofits | 6 | $55.6 million |
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| 81 | Blue Ridge Community Health Services, Inc. · Hendersonville | Other | 11 | $55.4 million |
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| 82 | City of Concord · Concord | State and local governments | 52 | $55.1 million |
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| 83 | Western Carolina Community Action, Inc · Hendersonville | Nonprofits | 12 | $55.0 million |
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| 84 | North Carolina Department of Transportation · Garner | State and local governments | 31 | $53.8 million |
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| 85 | NC Commission on Volunteerism & Community Service · Raleigh | State and local governments | 17 | $51.7 million |
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| 86 | Guilford Technical Community College · Jamestown | Colleges and universities | 5 | $50.6 million |
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| 87 | City of Winston-Salem · Winston Salem | State and local governments | 18 | $49.1 million |
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| 88 | Wake County Public Schools · Cary | State and local governments | 11 | $48.5 million |
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| 89 | Lincoln Community Health Center Incorporated · Durham | Nonprofits | 10 | $48.1 million |
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| 90 | Asheville-Buncombe Community Christian Ministry, Inc · Arden | Nonprofits | 40 | $47.8 million |
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| 91 | Epicypher, Inc. · Research Triangle Park | Small businesses | 27 | $47.3 million |
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| 92 | Shaw University · Raleigh | Colleges and universities | 21 | $47.2 million |
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| 93 | Onslow County Schools · Jacksonville | State and local governments | 17 | $46.6 million |
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| 94 | Housing Authority of the City of Raleigh North Carolina · Raleigh | State and local governments | 89 | $46.4 million |
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| 95 | Wilmington Housing Authority · Wilmington | Tribal governments and organizations | 97 | $46.4 million |
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| 96 | Volunteers of America of the Carolinas, Inc. · Durham | Nonprofits | 16 | $45.5 million |
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| 97 | Livingstone College, Inc. · Salisbury | Colleges and universities | 13 | $44.2 million |
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| 98 | Saint Augustine's University · Raleigh | Colleges and universities | 30 | $43.0 million |
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| 99 | Housing Authority of City of High Po · High Point | Tribal governments and organizations | 110 | $42.9 million |
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| 100 | Jones-Onslow Electric Membership Corp · Jacksonville | Other | 2 | $42.6 million |
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