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Grants / Department of Health and Human Services / National Institutes of Health

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

Open Closes November 10, 2026 (10 days left) Opportunity RFA-OD-27-009

National Institutes of Health is offering grants to nonprofits and colleges and universities. It expects to make about 5 awards worth $5.0 million in total. Applications close on November 10, 2026.

From the official notice on Grants.gov, last changed September 24, 2026. Checked October 31, 2026.

Key dates

PostedSeptember 24, 2026
DeadlineNovember 10, 2026
Archived by Grants.govJanuary 10, 2027

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Who can apply

This opportunity is open to nonprofits and colleges and universities.

The primary applicant organization must be a university or other research institution that participates in the NIH STTR program. Participation means that a university or other research institution has been a formal partner to a small business on an STTR award.

More grants for nonprofits, colleges and universities.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with the funds to seed the creation of academic entrepreneurship Hubs. Hubs will be responsible for providing innovators with both the initial investment and resources to support the proof-of-concept work and the mentorship in product development and commercialization needed to develop high priority technologies within the NIH's mission. Funded Hubs are intended to work as a consortium to enable: (1) the infrastructure for identifying the most promising technologies, (2) funding for product definition studies (e.g. feasibility studies, prototype development, proof-of-concept studies) provided to individual researchers, (3) access to resources and expertise in areas required for early stage technology development (including scientific, regulatory, reimbursement, business, legal, and project management), and (4) skills development and hands-on experience in entrepreneurship. Establishing public-private partnerships and providing additional non-federal funds will be critical for success. This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to National Institutes of Health, nihreach@nih.gov, 301-402-2541.

Open the official notice

Questions people ask

Who can apply for Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits and colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)?

Closes November 10, 2026 (10 days left). Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

About $5.0 million in total across about 5 awards.

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