Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

Investigator-Focused Award (Parent R35)

Forecast Expected deadline October 4, 2027 Opportunity PAR-28-037

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around May 27, 2027, with applications due around October 4, 2027.

From the official notice on Grants.gov, last changed July 30, 2026. Checked October 31, 2026.

Key dates

Forecast postedJuly 30, 2026
Expected postingMay 27, 2027
Expected deadlineOctober 4, 2027
Expected award dateJuly 1, 2028

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

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Is this a realistic fit?

What the grant funds

The National Institutes of Health intends to publish a Parent R35 "Investigator-Focused Award" Notice of Funding Opportunity (NOFO) to fund research programs for investigators at all career stages, including Early Stage Investigators (ESIs). The Parent R35 Investigator-Focused Award is intended to provide support for an investigator's program of research within the mission of the awarding Institute or Center (IC) rather than support for a pre-defined project with specific aims. The R35 is typically expected to be an investigator's primary (or only) source of research funding from the awarding IC. An R35 award gives investigators funding stability and scientific freedom. With R35 support, researchers can pursue ambitious and innovative studies without the pressure of constantly seeking new funding streams. Key benefits include: Providing flexibility to follow the science as it evolves within the awarding IC's mission. Providing stability to take on important, challenging research questions. Allowing recipients to devote sufficient time to research, mentoring, and scientific service, and less time to grant administration. Providing a high potential for scientific breakthroughs by enabling investigators to think broadly and pursue promising opportunities.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to Office of Extramural Research, ParentR35@mail.nih.gov, Please contact via e-mail.

Open the official notice

Questions people ask

Who can apply for Investigator-Focused Award (Parent R35)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Investigator-Focused Award (Parent R35)?

Expected deadline October 4, 2027. Confirm the date and time in the official notice on Grants.gov.

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