Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

RFA-NS-21-029: HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)

Closed Closed October 10, 2023 Opportunity RFA-NS-21-029

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on October 10, 2023.

From the official notice on Grants.gov, last changed June 8, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-NS-21-029 were run by National Institute of Neurological Disorders and Stroke (NINDS, 14 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

This notice replaced RFA-NS-21-016.

Application due dates, page limits and budget limits are set in the notice. Read RFA-NS-21-029 in the NIH Guide.

Key dates

PostedJune 8, 2021
DeadlineOctober 10, 2023
Archived by Grants.govNovember 15, 2023

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

Reissue of RFA-NS-21-016: The goal of this funding opportunity announcement (FOA) is to solicit Initial Analgesic Development R61 applications that propose 2-year exploratory/planning awards that are expected to enable a future application for RFA-NS-21-015 HEAL Initiative: Team Research - for Initial Translational Efforts in Non-addictive Analgesic Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed). Thus, the limited scope of aims and approach of these applications are expected to establish a strong research team, feasibility, validity, or other technically qualifying results that support, enable, and/or lay the groundwork for a subsequent Team Research U19 application. These R61 awards will support the building of a research team to collect initial data and recruit additional collaborators. The proposal must include a plan for developing a strong research team, as well as a strategy to collect preliminary data linking putative therapeutic targets to the proposed pain indication and supporting the hypothesis that altering target activity will produce desirable outcomes for the disease.

Category: Health, Income Security and Social Services.

Funded under RFA-NS-21-029 so far

NIH funded 14 projects under RFA-NS-21-029 in fiscal 2022 to 2024, at 12 institutions. The median yearly award was $1.6 million.

Most projects: Washington University (Missouri), 2, Duke University (North Carolina), 2, Saint Louis University (Missouri), 1, Schepens Eye Research Institute (Massachusetts), 1, Research Triangle Institute (North Carolina), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before

From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts203$288 million
The Regents of the University of California, San FranciscoCalifornia248$277 million
The Johns Hopkins UniversityMaryland230$276 million
The Trustees of Columbia University in the City of New YorkNew York188$226 million
Regents of the University of MichiganMichigan179$221 million

Top states: California ($1.4 billion), New York ($926 million), Massachusetts ($906 million), Pennsylvania ($626 million), Texas ($499 million).

Who has won Mental Health Research Grants grants before

From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Yale UnivConnecticut185$371 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania200$297 million
University of California, Los AngelesCalifornia176$234 million
Icahn School of Medicine at Mount SinaiNew York144$212 million
The Washington UniversityMissouri149$211 million

Top states: California ($1.4 billion), Massachusetts ($1.1 billion), New York ($1.1 billion), Pennsylvania ($667 million), Connecticut ($422 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-NS-21-029 still open?

No. It closed on October 10, 2023.

Who can apply for HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)?

Closed October 10, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under RFA-NS-21-029?

NIH RePORTER lists 14 projects funded under RFA-NS-21-029 in fiscal 2022 to 2024, at 12 institutions. The most were at Washington University, Duke University, Saint Louis University.

Who has won Oral Diseases and Disorders Research grants before?

The largest recipients over five fiscal years were Regents of the University of Michigan, The Regents of the University of California, San Francisco, University of Southern California. The program made 2,263 awards worth $1.9 billion in that time.

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