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Grants / Department of Health and Human Services / National Institutes of Health

PAR-25-202: Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed)

Closed Closed May 12, 2026 Opportunity PAR-25-202

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on May 12, 2026.

From the official notice on Grants.gov, last changed May 12, 2026. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-25-202 were run by National Institute of General Medical Sciences (NIGMS, 8 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-25-202 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-22-126March 21, 2022Closed November 22, 2024Closed

Key dates

PostedNovember 14, 2024
DeadlineMay 12, 2026
Archived by Grants.govJune 11, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO)supports exploratory research leading to proof of concept for the development of new technologies relevant to the NIGMS mission. Projects should entail a high degree of risk and/or novelty, and have a high future potential impact in biomedical research.

Category: Health.

Funded under PAR-25-202 so far

NIH funded 8 projects under PAR-25-202 in fiscal 2026, at 8 institutions. The median yearly award was $442,888.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-25-202 still open?

No. It closed on May 12, 2026.

Who can apply for Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed)?

Closed May 12, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-25-202?

NIH RePORTER lists 8 projects funded under PAR-25-202 in fiscal 2026, at 8 institutions. The most were at State University of Ny,binghamton, University of Rochester, Trustees of Indiana University.

Who has won Biomedical Research and Research Training grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, Regents of the University of Michigan, University of California, San Diego. The program made 11,631 awards worth $15 billion in that time.

Similar open grants