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Grants / Department of Health and Human Services / National Institutes of Health

PAR-24-065: NHLBI Program Project Applications (P01 Clinical Trials Optional)

Closed Closed September 25, 2026 Opportunity PAR-24-065

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on September 25, 2026.

From the official notice on Grants.gov, last changed November 20, 2023. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-24-065 were run by National Heart Lung and Blood Institute (NHLBI, 22 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-24-065 in the NIH Guide.

Key dates

PostedNovember 20, 2023
DeadlineSeptember 25, 2026
Archived by Grants.govOctober 31, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The projects may be supported by core units, if justified, to facilitate economy of effort, space, and equipment. The NHLBI provides support for Program Project Grants (PPGs) in the belief that collaborative research efforts can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects that have no interaction or thematic integration. NHLBI is particularly interested in encouraging new scientific directions in PPGs. Use of the P01 activity code is viewed as an opportunity to attract scientists who have not traditionally been supported by the NHLBI. Further, the PPG environment presents an opportunity for emerging scientific leaders to gain insight into how to lead a successful scientific Program, and applicants will have the opportunity to include a project led by an Early Stage Investigator (ESI). All projects in the Program must be interrelated and have objectives that address a central theme within the scientific mandate of the NHLBI.

Category: Health.

Funded under PAR-24-065 so far

NIH funded 22 projects under PAR-24-065 in fiscal 2025 to 2026, at 21 institutions. The median yearly award was $390,132.

Most projects: Washington University (Missouri), 2, Massachusetts General Hospital (Massachusetts), 1, Cleveland Clinic Lerner Com-Cwru (Ohio), 1, Medical College of Wisconsin (Wisconsin), 1, New York University School of Medicine (New York), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
CORE 1: Cellular diagnostics/imaging core P01Massachusetts General Hospital2026$342,143
Gut Microbiota and Cardiometabolic Diseases P01Cleveland Clinic Lerner Com-Cwru2026$2.4 million
Core B: Surgery and Histology Core P01Medical College of Wisconsin2026$255,589
Project 2 Title: Diabetes, RAGE/DIAPH1 and Limb Ischemia P01New York University School of Medicine2026$549,096
Administrative Core P01Children's Hosp of Philadelphia2026$452,152
Cellular Mechanisms of Inflammation, Hemostasis, and Thrombosis P01University of California, San Diego2026$2.4 million
Wildfire Exposure: Cardiovascular and Airway Inflammation Research (WE-CAIR) P01University of California at Davis2026$2.8 million
Project 2 P01University of Iowa2026$383,704

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Lung Diseases Research grants before

From fiscal 2021 to 2025, Lung Diseases Research (93.838) awarded $8.7 million across 5 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts1$5.4 million
New England Research Institutes IncMassachusetts1$2.7 million
The Trustees of the University of PennsylvaniaPennsylvania1$355,699
University of WashingtonWashington1$350,272
The Trustees of Columbia University in the City of New YorkNew York1$319,659

Top states: Massachusetts ($7.8 million), Washington ($350,272), New York ($319,659), Pennsylvania ($300,836).

Who has won Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders grants before

From fiscal 2021 to 2025, Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders (93.840) awarded $3.3 million across 9 grant awards, an average of $364,164 per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of ColoradoColorado1$1.5 million
Indiana Department of HealthIndiana1$558,986
Minnesota Department of HealthMinnesota1$442,754
Michigan Public Health InstituteMichigan1$311,837
City of PhiladelphiaPennsylvania1$251,231

Top states: Colorado ($1.5 million), Indiana ($558,986), Minnesota ($442,754), Michigan ($311,837), South Carolina ($191,177).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-24-065 still open?

No. It closed on September 25, 2026.

Who can apply for NHLBI Program Project Applications (P01 Clinical Trials Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NHLBI Program Project Applications (P01 Clinical Trials Optional)?

Closed September 25, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-24-065?

NIH RePORTER lists 22 projects funded under PAR-24-065 in fiscal 2025 to 2026, at 21 institutions. The most were at Washington University, Massachusetts General Hospital, Cleveland Clinic Lerner Com-Cwru.

Who has won Cardiovascular Diseases Research grants before?

The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, Regents of the University of Michigan. The program made 11,798 awards worth $15 billion in that time.

Similar open grants