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Grants / Department of Health and Human Services / National Institutes of Health

NIH Research Program Projects (Parent P01 Clinical Trial Optional)

Open Closes May 25, 2029 (937 days left) Opportunity PA-27-061

National Institutes of Health is offering grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications close on May 25, 2029.

From the official notice on Grants.gov, last changed October 14, 2026. Checked October 31, 2026.

Key dates

PostedOctober 14, 2026
DeadlineMay 25, 2029
Archived by Grants.govJuly 25, 2029

Add the deadline to your calendar

Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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Is this a realistic fit?

What the grant funds

Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) invite applications for the investigator-initiated Program Project (P01). A P01 supports a broadly based, multidisciplinary research program with a specific major scientific objective or theme. The proposed Program Projects are focused on the programmatic interests of one or more of the participating ICOs based on their scientific missions. A program project utilizes research projects with a common central scientific theme, an administrative core, and optional shared resource core(s) to accomplish ICOs' programmatic objectives.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to National Institutes of Health, 301-402-2541.

Open the official notice

Questions people ask

Who can apply for NIH Research Program Projects (Parent P01 Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIH Research Program Projects (Parent P01 Clinical Trial Optional)?

Closes May 25, 2029 (937 days left). Confirm the date and time in the official notice on Grants.gov.

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