Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PAR-23-219: SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)

Closed Closed September 5, 2025 Opportunity PAR-23-219

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.

National Institutes of Health offered grants to small businesses. Applications closed on September 5, 2025.

From the official notice on Grants.gov, last changed April 3, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-23-219 were run by National Heart Lung and Blood Institute (NHLBI, 16 projects), National Institute of Allergy and Infectious Diseases (NIAID, 10 projects), National Institute on Aging (NIA, 7 projects) and National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, 5 projects), and 11 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-23-219 in the NIH Guide.

Key dates

PostedJuly 12, 2023
DeadlineSeptember 5, 2025
Archived by Grants.govOctober 5, 2025

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

More grants for small businesses.

Is this a realistic fit?

What the grant funds

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications from small business concerns (SBCs) to the newly re-authorized Commercialization Readiness Pilot (CRP) program. The NOFO aims to facilitate the transition of previously or currently funded SBIR and STTR Phase II and Phase IIB projects to the commercialization stage by providing additional support for technical assistance and later stage research and development (R and D) not typically supported through Phase II or Phase IIB grants or contracts. This may include independent replication of key studies, Investigational New Drug (IND)-enabling studies, clinical studies, manufacturing costs, regulatory assistance, or a combination of services. Although a significant amount of the work in a CRP award may be subcontracted to other institutions, the Small Business Concern (SBC) is expected to maintain oversight and management of the R and D throughout the award. Clinical Trials are not accepted under this NOFO.

Category: Education, Environment, Food and Nutrition, Health.

Funded under PAR-23-219 so far

NIH funded 62 projects under PAR-23-219 in fiscal 2024 to 2026, at 60 institutions. The median yearly award was $906,297.

Most projects: Aventusoft, LLC (Florida), 2, Starlight Cardiovascular, Inc. (California), 2, Vantis Vascular Inc (Michigan), 1, Moonlight Therapeutics, Inc. (Georgia), 1, Aplos Medical Inc (Minnesota), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before

From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Regents of the University of MichiganMichigan273$345 million
The Trustees of the University of PennsylvaniaPennsylvania187$272 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania209$238 million
The Washington UniversityMissouri187$227 million
The Regents of the University of California, San FranciscoCalifornia176$208 million

Top states: California ($1.2 billion), Massachusetts ($932 million), New York ($798 million), Pennsylvania ($762 million), Texas ($482 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-23-219 still open?

No. It closed on September 5, 2025.

Who can apply for SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)?

Closed September 5, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-23-219?

NIH RePORTER lists 62 projects funded under PAR-23-219 in fiscal 2024 to 2026, at 60 institutions. The most were at Aventusoft, LLC, Starlight Cardiovascular, Inc., Vantis Vascular Inc.

Who has won Environmental Health grants before?

The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.

Similar open grants