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Grants / Department of Health and Human Services / National Institutes of Health

PAR-23-063: Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)

Closed Closed May 28, 2025 Opportunity PAR-23-063

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $1.5 million to small businesses. Applications closed on May 28, 2025.

From the official notice on Grants.gov, last changed December 20, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-23-063 were run by National Institute of General Medical Sciences (NIGMS, 27 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-23-063 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-22-163April 19, 2022Closed September 27, 2022Closed

Key dates

PostedDecember 20, 2022
DeadlineMay 28, 2025
Archived by Grants.govJuly 3, 2025

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. See full Funding Opportunity Announcement for additional details on eligibility

More grants for small businesses.

Is this a realistic fit?

What the grant funds

The Centers of Biomedical Research Excellence (COBRE) program supports the establishment and development of innovative biomedical and behavioral research centers at Institutional Development Award (IDeA)-eligible institutions through awards for three sequential five-year phases. The purpose of the COBRE Phase 2 award is to strengthen successful COBRE Phase 1 centers established in Phase 1 through further improvements to research infrastructure and the continued development of a critical mass of investigators with shared scientific interests who are able to compete effectively for independent research funding and further improvements to research infrastructure at the institution.

Category: Health.

Funded under PAR-23-063 so far

NIH funded 27 projects under PAR-23-063 in fiscal 2024 to 2026, at 26 institutions. The median yearly award was $273,875.

Most projects: University of Oklahoma HLTH Sciences Ctr (Oklahoma), 2, University of Nevada Reno (Nevada), 1, Mainehealth (Maine), 1, Emma Pendleton Bradley Hospital (Rhode Island), 1, University of New Mexico Health Scis Ctr (New Mexico), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
Core A - Administrative Core P20University of Nevada Reno2026$632,877
Phase 2 Center of Biomedical Research Excellence in Acute Care Research and Rural Health P20Mainehealth2026$2.7 million
An initial test of biobehavioral mechanisms of sleep health alterations in the context of adolescent cannabis use using objective methods P20Emma Pendleton Bradley Hospital2026$199,064
University of New Mexico Center for Metals in Biology and Medicine P20University of New Mexico Health Scis Ctr2026$2.3 million
Intervention Support Core P20University of Montana2026$379,423
COBRE-DIABETES P20University of Hawaii at Manoa2026$2.3 million
Oklahoma Center for Microbial Pathogenesis and Immunity P20University of Oklahoma HLTH Sciences Ctr2026$2.2 million
Molecular Mechanisms P20LSU Pennington Biomedical Research Ctr2026$475,916

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-23-063 still open?

No. It closed on May 28, 2025.

Who can apply for Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)?

Closed May 28, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $1.5 million each.

Who has been funded under PAR-23-063?

NIH RePORTER lists 27 projects funded under PAR-23-063 in fiscal 2024 to 2026, at 26 institutions. The most were at University of Oklahoma HLTH Sciences Ctr, University of Nevada Reno, Mainehealth.

Who has won Biomedical Research and Research Training grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, Regents of the University of Michigan, University of California, San Diego. The program made 11,631 awards worth $15 billion in that time.

Similar open grants