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Grants / Department of Health and Human Services / National Institutes of Health

PAR-22-163: Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)

Closed Closed September 27, 2022 Opportunity PAR-22-163

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $1.5 million to small businesses. Applications closed on September 27, 2022.

From the official notice on Grants.gov, last changed April 19, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-163 were run by National Institute of General Medical Sciences (NIGMS, 11 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-163 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-23-063December 20, 2022Closed May 28, 2025Closed

Key dates

PostedApril 19, 2022
DeadlineSeptember 27, 2022
Archived by Grants.govNovember 2, 2022

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. See Full Announcement for additional Eligibility Details

More grants for small businesses.

Is this a realistic fit?

What the grant funds

The National Institute of General Medical Sciences (NIGMS) invites applications for renewal of eligible Centers of Biomedical Research Excellence (COBRE) grants. The objective of the COBRE initiative is to strengthen an institution's biomedical research infrastructure through the establishment of a thematic, multi-disciplinary center and to enhance the ability of investigators to compete independently for NIH individual research grants or other external peer-reviewed support. COBRE awards are supported through the Institutional Development Award (IDeA) Program, which aims to foster health-related research by increasing the competitiveness of investigators at institutions located in states with historically low aggregate success rates for grant awards from the NIH. The goal of this FOA is to support existing COBRE Phase 1 Centers by further strengthening the research infrastructure and to continue the development and support of a critical mass of investigators with the expertise in the Center's scientific interest areas.

Category: Health.

Funded under PAR-22-163 so far

NIH funded 11 projects under PAR-22-163 in fiscal 2023 to 2026, at 11 institutions. The median yearly award was $266,774.

Recently funded projects
ProjectInstitutionFiscal yearAward
Longitudinal Networks Core P20University of Nebraska Lincoln2026$655,844
COBRE Center on Opioids and Overdose P20Rhode Island Hospital2026$2.1 million
Determinants of Microbiome Stability Following Pathogen Infection P20University of Hawaii at Manoa2026$162,891
Administrative Core P20Clemson University2026$786,755
CIBBR Administrative Core P20University of New Hampshire2026$1.4 million
Single-Cell and Spatial Transcriptomics Core P20University of Nebraska Medical Center2026$84,244
Administrative Core P20University of Vermont & St Agric College2026$1.2 million
NeuroMAP Phase II - Recruitment and Assessment Core P20Laureate Institute for Brain Research2026$245,905

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-163 still open?

No. It closed on September 27, 2022.

Who can apply for Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Limited Competition: Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) (P20 - Clinical Trial Optional)?

Closed September 27, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $1.5 million each.

Who has been funded under PAR-22-163?

NIH RePORTER lists 11 projects funded under PAR-22-163 in fiscal 2023 to 2026, at 11 institutions. The most were at University of Nebraska Lincoln, Rhode Island Hospital, University of Hawaii at Manoa.

Who has won Biomedical Research and Research Training grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, Regents of the University of Michigan, University of California, San Diego. The program made 11,631 awards worth $15 billion in that time.

Similar open grants