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Grants / Department of Health and Human Services / National Institutes of Health

PAR-22-130: NIA Program Project Applications (P01 Clinical Trial Optional)

Closed Closed January 7, 2026 Opportunity PAR-22-130

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on January 7, 2026.

From the official notice on Grants.gov, last changed May 21, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-22-130 were run by National Institute on Aging (NIA, 20 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-22-130 in the NIH Guide.

Key dates

PostedMarch 10, 2022
DeadlineJanuary 7, 2026
Archived by Grants.govFebruary 6, 2026

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The National Institute on Aging (NIA) invites the submission of investigator-initiated research program project (P01) applications addressing scientific areas relevant to NIA's mission. Each application submitted to this Funding opportunity announcement (FOA) must include at least three related research projects that share a common central theme, focus, overall objective, and an administrative core to lead the project.?Revision applications should include expansion of an existing, or proposal of a new, project(s) within the context and theme of the parent P01 award. Revision applications may not request support beyond the end date of the parent P01 award, but may propose to expand existing cores, or propose new cores, to support the expansion or creation of new projects.

Category: Health.

Funded under PAR-22-130 so far

NIH funded 20 projects under PAR-22-130 in fiscal 2023 to 2026, at 17 institutions. The median yearly award was $482,732.

Most projects: University of Pennsylvania (Pennsylvania), 3, Columbia University Health Sciences (New York), 2, Mayo Clinic Rochester (Minnesota), 1, Icahn School of Medicine at Mount Sinai (New York), 1, Northwestern University (Illinois), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
From Molecules To Complex Syndromes: Using Networks to Understand Heterogeneity in FTD-TDP and Aging P01University of Pennsylvania2026$3.2 million
Project 1: Epigenetic control of cell identity and inflammation in aging P01University of Pennsylvania2026$401,405
Core A - Administrative and Systems Biology of Aging Core (ASBC) P01Mayo Clinic Rochester2026$360,805
Administrative Resource Core P01Icahn School of Medicine at Mount Sinai2026$667,043
Core C: Modeling Core P01Northwestern University2026$469,563
Project 1: The City Partners Brain Health Study (COMPASS): Plasma Biomarkers of Alzheimer Disease in a Population-Representative Cohort P01Washington University2026$694,153
Administration P01Johns Hopkins University2026$235,750
Core C: Resource Core P01University of Pennsylvania2026$445,427

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-22-130 still open?

No. It closed on January 7, 2026.

Who can apply for NIA Program Project Applications (P01 Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for NIA Program Project Applications (P01 Clinical Trial Optional)?

Closed January 7, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-22-130?

NIH RePORTER lists 20 projects funded under PAR-22-130 in fiscal 2023 to 2026, at 17 institutions. The most were at University of Pennsylvania, Columbia University Health Sciences, Mayo Clinic Rochester.

Who has won Aging Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, The Trustees of Columbia University in the City of New York, University of Southern California. The program made 11,026 awards worth $19 billion in that time.

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