Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-357: Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)

Closed Closed January 7, 2025 Opportunity PAR-21-357

This grant is closed. A newer notice from the same program is open now: Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) (PAR-27-078). Status: Due dates in the notice, expires October 25, 2027. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants of up to $300,000 to colleges and universities. Applications closed on January 7, 2025.

From the official notice on Grants.gov, last changed January 10, 2022. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-357 were run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, 7 projects), National Institute on Aging (NIA, 3 projects), National Institute on Deafness and Other Communication Disorders (NIDCD, 2 projects) and National Institute of Mental Health (NIMH, 2 projects), and 2 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-357 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-27-078May 29, 2026Due dates in the notice, expires October 25, 2027Open

Key dates

PostedJanuary 10, 2022
DeadlineJanuary 7, 2025
Archived by Grants.govFebruary 12, 2025

Who can apply

This opportunity was open to colleges and universities.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for colleges and universities.

Is this a realistic fit?

What the grant funds

The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.

Category: Education, Health, Income Security and Social Services.

Funded under PAR-21-357 so far

NIH funded 16 projects under PAR-21-357 in fiscal 2023 to 2025, at 15 institutions. The median yearly award was $442,954.

Most projects: Baylor University (Texas), 2, Arcadia University (Pennsylvania), 1, Merrimack College (Massachusetts), 1, California State University San Marcos (California), 1, Villanova University (Pennsylvania), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Who has won Cardiovascular Diseases Research grants before

From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Trustees of the University of PennsylvaniaPennsylvania313$380 million
Brigham & Womens Hospital IncMassachusetts274$374 million
Regents of the University of MichiganMichigan277$355 million
The Trustees of Columbia University in the City of New YorkNew York207$335 million
University of Pittsburgh - of the Commonwealth System of Higher EducationPennsylvania295$320 million

Top states: California ($1.8 billion), Massachusetts ($1.5 billion), New York ($1.4 billion), Pennsylvania ($1.1 billion), Ohio ($749 million).

Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before

From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The General Hospital CorporationMassachusetts203$288 million
The Regents of the University of California, San FranciscoCalifornia248$277 million
The Johns Hopkins UniversityMaryland230$276 million
The Trustees of Columbia University in the City of New YorkNew York188$226 million
Regents of the University of MichiganMichigan179$221 million

Top states: California ($1.4 billion), New York ($926 million), Massachusetts ($906 million), Pennsylvania ($626 million), Texas ($499 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-27-078, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-357 still open?

No. It closed on January 7, 2025. A newer notice is open: PAR-27-078, due dates in the notice, expires October 25, 2027.

Who can apply for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)?

National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)?

Closed January 7, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $300,000 each.

Who has been funded under PAR-21-357?

NIH RePORTER lists 16 projects funded under PAR-21-357 in fiscal 2023 to 2025, at 15 institutions. The most were at Baylor University, Arcadia University, Merrimack College.

Who has won Human Genome Research grants before?

The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.

Similar open grants