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Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-225: Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)

Closed Closed January 5, 2025 Opportunity PAR-21-225

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants to small businesses. Applications closed on January 5, 2025.

From the official notice on Grants.gov, last changed June 6, 2024. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-225 were run by NIH Office of the Director (OD, 14 projects) and National Institute of Mental Health (NIMH, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-225 in the NIH Guide.

Key dates

PostedApril 30, 2021
DeadlineJanuary 5, 2025
Archived by Grants.govFebruary 4, 2025

Who can apply

This opportunity was open to small businesses.

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

More grants for small businesses.

Is this a realistic fit?

What the grant funds

This funding opportunity announcement (FOA) encourages applications from small business concerns (SBCs) for Small Business Innovation Research (SBIR) projects to develop novel tools and devices to improve handling of laboratory animals, to ease the management of animal facilities, and to enhance experiments which use animal models. The intent is to facilitate the design, implementation, and creation of tools and devices to directly benefit the welfare of research animals, and to advance equipment to improve infrastructure and environmental conditions of animal facilities that support biomedical and bio-behavioral research.

Category: Health.

Funded under PAR-21-225 so far

NIH funded 15 projects under PAR-21-225 in fiscal 2022 to 2026, at 13 institutions. The median yearly award was $395,558.

Most projects: Paratechs Corp. (Kentucky), 3, Spoc Proteomics Inc. (Arizona), 1, Nemametrix, Inc. (Oregon), 1, Geegah LLC (New York), 1, Ora Biomedical, Inc. (Washington), 1.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Research Infrastructure Programs grants before

From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia27$102 million
Oregon Health & Science UniversityOregon18$92.1 million
University of WashingtonWashington7$79.5 million
Emory UniversityGeorgia14$78.3 million
The Administrators of Tulane Educational FundLouisiana10$68.0 million

Top states: California ($183 million), Texas ($127 million), Oregon ($111 million), Massachusetts ($90.4 million), Washington ($87.3 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-225 still open?

No. It closed on January 5, 2025.

Who can apply for Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)?

Closed January 5, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under PAR-21-225?

NIH RePORTER lists 15 projects funded under PAR-21-225 in fiscal 2022 to 2026, at 13 institutions. The most were at Paratechs Corp., Spoc Proteomics Inc., Nemametrix, Inc.

Who has won Research Infrastructure Programs grants before?

The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.

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