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Grants / Department of Health and Human Services / National Institutes of Health

PAR-21-173: Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)

Closed Closed January 7, 2024 Opportunity PAR-21-173

This grant is closed. A newer notice from the same program is open now: Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) (PAR-25-415). Status: Due dates in the notice, expires September 7, 2028. It is in our archive of National Institutes of Health notices from 2021.

National Institutes of Health offered grants of up to $125,000 to colleges and universities. Applications closed on January 7, 2024.

From the official notice on Grants.gov, last changed March 19, 2021. Checked November 7, 2026.

About this NIH notice

Projects funded under PAR-21-173 were run by National Institute of General Medical Sciences (NIGMS, 69 projects), National Institute of Allergy and Infectious Diseases (NIAID, 6 projects), National Heart Lung and Blood Institute (NHLBI, 3 projects) and National Institute of Neurological Disorders and Stroke (NINDS, 3 projects), and 3 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read PAR-21-173 in the NIH Guide.

Other notices with this title

National Institutes of Health has posted this title under other numbers: earlier or later rounds, or the same competition for another area. Each has its own dates and may change its rules.

NoticePostedDeadlineStatus
PAR-25-415June 13, 2025Due dates in the notice, expires September 7, 2028Open
PAR-24-145March 14, 2024Closed May 23, 2025Closed

Key dates

PostedMarch 18, 2021
DeadlineJanuary 7, 2024
Archived by Grants.govFebruary 12, 2024

Who can apply

This opportunity was open to colleges and universities.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

More grants for colleges and universities.

Is this a realistic fit?

What the grant funds

SuRE is a research capacity building program designed to develop and sustain research excellence in U.S. higher education institutions that receive limited NIH research support and serve students from groups underrepresented in biomedical research (see NOT-OD-20-031) with an emphasis on providing students with research opportunities and enriching the research environments at the applicant institutions. The purpose of SuRE-First awards is to support research grants for faculty investigators at eligible institutions who have not had prior independent external research grants.

Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services.

Funded under PAR-21-173 so far

NIH funded 85 projects under PAR-21-173 in fiscal 2022 to 2026, at 55 institutions. The median yearly award was $183,125.

Most projects: University of Nevada Las Vegas (Nevada), 6, St. John's University (New York), 4, Rochester Institute of Technology (New York), 4, San Jose State University (California), 4, California State University Northridge (California), 4.

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Allergy and Infectious Diseases Research grants before

From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Fred Hutchinson Cancer CenterWashington85$938 million
Duke UniversityNorth Carolina230$781 million
University of California, Los AngelesCalifornia138$745 million
The Johns Hopkins UniversityMaryland321$668 million
Emory UniversityGeorgia282$650 million

Top states: California ($3.4 billion), Massachusetts ($2.1 billion), Washington ($1.9 billion), New York ($1.8 billion), North Carolina ($1.5 billion).

Who has won Aging Research grants before

From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Regents of the University of California, San FranciscoCalifornia337$575 million
The Trustees of Columbia University in the City of New YorkNew York242$574 million
University of Southern CaliforniaCalifornia203$572 million
The Washington UniversityMissouri210$556 million
Regents of the University of MichiganMichigan232$538 million

Top states: California ($3.4 billion), New York ($2.0 billion), Massachusetts ($1.8 billion), Pennsylvania ($1.0 billion), Texas ($912 million).

Who has won Biomedical Research and Research Training grants before

From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
The Leland Stanford Junior UniversityCalifornia186$290 million
Regents of the University of MichiganMichigan226$268 million
University of California, San DiegoCalifornia198$264 million
Yale UnivConnecticut195$250 million
University of Wisconsin SystemWisconsin169$241 million

Top states: California ($2.1 billion), New York ($1.4 billion), Massachusetts ($971 million), Texas ($833 million), Pennsylvania ($680 million).

Other programs behind this notice

Applying now

This notice no longer takes applications. Apply under the newer notice, PAR-25-415, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is PAR-21-173 still open?

No. It closed on January 7, 2024. A newer notice is open: PAR-25-415, due dates in the notice, expires September 7, 2028.

Who can apply for Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.

What is the deadline for Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)?

Closed January 7, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $125,000 each.

Who has been funded under PAR-21-173?

NIH RePORTER lists 85 projects funded under PAR-21-173 in fiscal 2022 to 2026, at 55 institutions. The most were at University of Nevada Las Vegas, St. John's University, Rochester Institute of Technology.

Who has won Environmental Health grants before?

The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.

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