PAR-21-173: Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
Closed
This grant is closed. A newer notice from the same program is open now: Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) (PAR-25-415). Status: Due dates in the notice, expires September 7, 2028. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants of up to $125,000 to colleges and universities. Applications closed on January 7, 2024.
From the official notice on Grants.gov, last changed March 19, 2021. Checked November 7, 2026.
- Award ceiling$125,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR16
- Clinical trialsNot allowed
- Funded byNIGMS, NIAID, NHLBI
- Median yearly award$183,125
- Typical project length4 years
- R16, Support for Research Excellence. Research at institutions with limited NIH funding, to build their research capacity. Other open R16 notices.
Projects funded under PAR-21-173 were run by National Institute of General Medical Sciences (NIGMS, 69 projects), National Institute of Allergy and Infectious Diseases (NIAID, 6 projects), National Heart Lung and Blood Institute (NHLBI, 3 projects) and National Institute of Neurological Disorders and Stroke (NINDS, 3 projects), and 3 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-21-173 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-25-415 | June 13, 2025 | Due dates in the notice, expires September 7, 2028 | Open |
| PAR-24-145 | March 14, 2024 | Closed May 23, 2025 | Closed |
Key dates
| Posted | March 18, 2021 |
|---|---|
| Deadline | January 7, 2024 |
| Archived by Grants.gov | February 12, 2024 |
Who can apply
This opportunity was open to colleges and universities.
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $183,125; it allows up to $125,000 per award.
- Most of the money in the 16 programs behind this notice (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
SuRE is a research capacity building program designed to develop and sustain research excellence in U.S. higher education institutions that receive limited NIH research support and serve students from groups underrepresented in biomedical research (see NOT-OD-20-031) with an emphasis on providing students with research opportunities and enriching the research environments at the applicant institutions. The purpose of SuRE-First awards is to support research grants for faculty investigators at eligible institutions who have not had prior independent external research grants.
Funded under PAR-21-173 so far
NIH funded 85 projects under PAR-21-173 in fiscal 2022 to 2026, at 55 institutions. The median yearly award was $183,125.
Who has won Allergy and Infectious Diseases Research grants before
From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Fred Hutchinson Cancer Center | Washington | 85 | $938 million |
| Duke University | North Carolina | 230 | $781 million |
| University of California, Los Angeles | California | 138 | $745 million |
| The Johns Hopkins University | Maryland | 321 | $668 million |
| Emory University | Georgia | 282 | $650 million |
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
Who has won Biomedical Research and Research Training grants before
From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 186 | $290 million |
| Regents of the University of Michigan | Michigan | 226 | $268 million |
| University of California, San Diego | California | 198 | $264 million |
| Yale Univ | Connecticut | 195 | $250 million |
| University of Wisconsin System | Wisconsin | 169 | $241 million |
Other programs behind this notice
- Diabetes, Digestive, and Kidney Diseases Extramural Research
- Extramural Research Programs in the Neurosciences and Neurological Disorders
- Drug Use and Addiction Research Programs
- Child Health and Human Development Extramural Research
- Vision Research
- Alcohol Research Programs
- Human Genome Research
- Environmental Health
- Research Related to Deafness and Communication Disorders
- Oral Diseases and Disorders Research
- Discovery and Applied Research for Technological Innovations to Improve Human Health
- Cancer Research Manpower
- Nursing Research
Applying now
This notice no longer takes applications. Apply under the newer notice, PAR-25-415, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-21-173 still open?
No. It closed on January 7, 2024. A newer notice is open: PAR-25-415, due dates in the notice, expires September 7, 2028.
Who can apply for Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)?
Closed January 7, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $125,000 each.
Who has been funded under PAR-21-173?
NIH RePORTER lists 85 projects funded under PAR-21-173 in fiscal 2022 to 2026, at 55 institutions. The most were at University of Nevada Las Vegas, St. John's University, Rochester Institute of Technology.
Who has won Environmental Health grants before?
The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.
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