PAR-21-169: Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
Closed
This grant is closed. A newer notice from the same program is open now: Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) (PAR-25-414). Status: Due dates in the notice, expires September 7, 2028. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants of up to $100,000 to colleges and universities. Applications closed on September 7, 2023.
From the official notice on Grants.gov, last changed March 19, 2021. Checked November 7, 2026.
- Award ceiling$100,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR16
- Clinical trialsNot allowed
- Funded byNIGMS, NINDS, NIAID
- Median yearly award$147,056
- Typical project length4 years
- R16, Support for Research Excellence. Research at institutions with limited NIH funding, to build their research capacity. Other open R16 notices.
Projects funded under PAR-21-169 were run by National Institute of General Medical Sciences (NIGMS, 127 projects), National Institute of Neurological Disorders and Stroke (NINDS, 14 projects), National Institute of Allergy and Infectious Diseases (NIAID, 11 projects) and National Institute on Drug Abuse (NIDA, 2 projects), and 3 more. Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read PAR-21-169 in the NIH Guide.
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| PAR-25-414 | June 13, 2025 | Due dates in the notice, expires September 7, 2028 | Open |
| PAR-24-144 | March 14, 2024 | Closed May 23, 2025 | Closed |
Key dates
| Posted | March 18, 2021 |
|---|---|
| Deadline | September 7, 2023 |
| Archived by Grants.gov | October 13, 2023 |
Who can apply
This opportunity was open to colleges and universities.
- Public and State controlled institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $147,056; it allows up to $100,000 per award.
- Most of the money in the 15 programs behind this notice (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
SuRE is a research capacity building program designed to develop and sustain research excellence in U.S. higher education institutions that receive limited NIH research support and serve students from groups underrepresented in biomedical research NOT-OD-20-031 with an emphasis on providing students with research opportunities and enriching the research environment at the applicant institutions. ?The purpose of SuRE awards is to provide research grant support for faculty investigators at eligible institutions who haveprior experience in leading externally-funded, independent research butare not currently funded by any NIH Research Project Grants with the exception of SuRE or SuRE-First awards.
Funded under PAR-21-169 so far
NIH funded 157 projects under PAR-21-169 in fiscal 2022 to 2026, at 67 institutions. The median yearly award was $147,056.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| The effects of eating a high fat diet on the therapeutic and abuse-related effects of morphine | University of Texas El Paso | 2026 | $151,360 |
| Targeting PARP Proteins in electronic cigarettes-induced cardiac dysfunction | Charles R. Drew University of Med & Sci | 2026 | $144,500 |
| Molecular mechanisms underlying renal lipotoxicity and DKD progression | Morehouse School of Medicine | 2026 | $142,000 |
| Assessment of small molecules as covalent inhibitors of Rac/Cdc42 | University of Puerto Rico Med Sciences | 2026 | $149,000 |
| The Enteric Glia as a Possible Target for Symptom Relief in Endometriosis | Ponce School of Medicine | 2026 | $156,800 |
| Regulation of mRNA homeostasis by PD-L1 | St. John's University | 2026 | $164,000 |
| Development and characterization of anti-P. gingivalis peptides | Meharry Medical College | 2026 | $145,500 |
| Mechanistic understanding of role of ATF2 signaling in radiation-induced esophageal cancer | University of Nevada Las Vegas | 2026 | $151,500 |
Who has won Allergy and Infectious Diseases Research grants before
From fiscal 2021 to 2025, Allergy and Infectious Diseases Research (93.855) awarded $22 billion across 13,282 grant awards, an average of $1.6 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Fred Hutchinson Cancer Center | Washington | 85 | $938 million |
| Duke University | North Carolina | 230 | $781 million |
| University of California, Los Angeles | California | 138 | $745 million |
| The Johns Hopkins University | Maryland | 321 | $668 million |
| Emory University | Georgia | 282 | $650 million |
Who has won Aging Research grants before
From fiscal 2021 to 2025, Aging Research (93.866) awarded $19 billion across 11,026 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Regents of the University of California, San Francisco | California | 337 | $575 million |
| The Trustees of Columbia University in the City of New York | New York | 242 | $574 million |
| University of Southern California | California | 203 | $572 million |
| The Washington University | Missouri | 210 | $556 million |
| Regents of the University of Michigan | Michigan | 232 | $538 million |
Who has won Biomedical Research and Research Training grants before
From fiscal 2021 to 2025, Biomedical Research and Research Training (93.859) awarded $15 billion across 11,631 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 186 | $290 million |
| Regents of the University of Michigan | Michigan | 226 | $268 million |
| University of California, San Diego | California | 198 | $264 million |
| Yale Univ | Connecticut | 195 | $250 million |
| University of Wisconsin System | Wisconsin | 169 | $241 million |
Other programs behind this notice
- Diabetes, Digestive, and Kidney Diseases Extramural Research
- Extramural Research Programs in the Neurosciences and Neurological Disorders
- Drug Use and Addiction Research Programs
- Child Health and Human Development Extramural Research
- Vision Research
- Alcohol Research Programs
- Human Genome Research
- Environmental Health
- Research Related to Deafness and Communication Disorders
- Oral Diseases and Disorders Research
- Discovery and Applied Research for Technological Innovations to Improve Human Health
- Nursing Research
Applying now
This notice no longer takes applications. Apply under the newer notice, PAR-25-414, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is PAR-21-169 still open?
No. It closed on September 7, 2023. A newer notice is open: PAR-25-414, due dates in the notice, expires September 7, 2028.
Who can apply for Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)?
Closed September 7, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $100,000 each.
Who has been funded under PAR-21-169?
NIH RePORTER lists 157 projects funded under PAR-21-169 in fiscal 2022 to 2026, at 67 institutions. The most were at University of Texas El Paso, University of Puerto Rico Med Sciences, San Jose State University.
Who has won Environmental Health grants before?
The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.
Similar open grants
- Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
- Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
- Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
- Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
- Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)