Grants for businesses in South Dakota
Federal agencies awarded $66.3 million in 14 grants to businesses in South Dakota from fiscal 2021 to 2025. The largest source was Partnerships for Climate-Smart Commodities. 770 federal grant opportunities are open or forecast now for businesses.
- South Dakota ranks 47th of the 50 states and DC for federal grants to businesses.
- Grants to businesses made up 0% of all federal grant money to recipients in South Dakota.
- That is 0% of all federal grant money to businesses nationwide.
- Awarded, FY 2021 to 2025$66.3 million
- Grant awards14
- Open now nationwide770
Federal programs that fund businesses in South Dakota
| Program | Awarded to businesses in South Dakota |
|---|---|
| Partnerships for Climate-Smart Commodities | $35.0 million |
| Integrative Activities | $12.4 million |
| Consolidated Rail Infrastructure and Safety Improvements | $10.6 million |
| GRRP | $4.8 million |
| Fossil Energy Research and Development | $1.1 million |
| Education Stabilization Fund | $1.1 million |
| Infrastructure and Investment Jobs Act Financial Assistance to Facilities that Purchase and Process Byproducts for Ecosystem Restoration | $1.0 million |
| Meat and Poultry Inspection Readiness Grants – Supplemental Funding | $200,000 |
| Organic Market Development Grant (OMDG) Program | $96,214 |
Open federal grants businesses can apply for
- Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
Open Closes November 2, 2026 (2 days left) - Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
Open Closes November 2, 2026 (2 days left) - BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA)
Open Closes November 2, 2026 (2 days left) - OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support
Open Closes November 2, 2026 (2 days left) - Topology
Open Closes November 3, 2026 (3 days left) - Geometric Analysis
Open Closes November 3, 2026 (3 days left) - DoW Reconstructive Transplant, Concept Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Idea Development Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Investigator-Initiated Research Award
Open Closes November 4, 2026 (4 days left) - DoW Bone Marrow Failure, Resource Development Award
Open Closes November 4, 2026 (4 days left) - DoW Reconstructive Transplant, Investigator-Initiated Research Award
Open Closes November 4, 2026 (4 days left) - Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed
Open Closes November 4, 2026 (4 days left) - Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
Open Closes November 5, 2026 (5 days left) - Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases
Open Closes November 5, 2026 (5 days left) - US Travelers Health Research, Surveillance, Communication, and Outreach Network
Open Closes November 5, 2026 (5 days left) - Request for Information - Gauging Investor Interest in the Development and Commercialization of Subsurface Energy Technologies
Open Closes November 5, 2026 (5 days left) - Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Open Closes November 6, 2026 (6 days left) - DoW Parkinson’s, Early Investigator Research Award
Open Closes November 6, 2026 (6 days left) - DoW Parkinson’s, Investigator-Initiated Research Award
Open Closes November 6, 2026 (6 days left) - Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)
Open Closes November 10, 2026 (10 days left) - Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
Open Closes November 10, 2026 (10 days left) - Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
Open Closes November 10, 2026 (10 days left) - Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
Open Closes November 10, 2026 (10 days left) - Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)
Open Closes November 10, 2026 (10 days left) - Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)
Open Closes November 10, 2026 (10 days left)
See all 770 open grants for businesses