Well Told Grants

Federal grant programs / Department of Health and Human Services

21st Century Cures Act - Precision Medicine Initiative (93.368)

Also known as All of Us Research Program

21st Century Cures Act - Precision Medicine Initiative (Assistance Listing 93.368) is run by the National Institutes of Health, part of the Department of Health and Human Services. It awarded $88.9 million in 36 grants from fiscal 2021 to 2025, about $2.5 million per award on average. 1 funding opportunity is open or forecast now.

The typical award was $191,737. Half of the 36 awards fell between $117,828 and $394,480, and they ranged from $81,000 to $68.9 million.

Key findings

What the program funds

To provide support for initiatives funded under the 21st Century Cures Act, the All of Us Research Program will gather data from one million or more diverse people living in the United States to accelerate research and improve health. By taking into account individual differences in lifestyle, environment, and biology, researchers will uncover paths toward delivering precision medicine.

From the federal Assistance Listing. Read the full listing on SAM.gov.

Open opportunities

Rules from the program listing

Who can apply

The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that applies and receives an award for support of research by a named principal investigator. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.

What the money can and cannot pay for

Other Transactions, Contracts, IAAs, Grants and cooperative agreements may be made to eligible institutions for the support of the All of Us Research Program projects. The awards may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and Facilities and Administrative Costs (formerly known as indirect costs).

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Quoted from the program's federal Assistance Listing. The notice of funding opportunity is the official source for each competition's rules.

Funding history and past recipients

From fiscal 2021 to 2025, 21st Century Cures Act - Precision Medicine Initiative (93.368) awarded $88.9 million across 36 grant awards, an average of $2.5 million per award.

Top states: Minnesota ($69.2 million), California ($12.3 million), Massachusetts ($1.8 million), Pennsylvania ($1.0 million), North Carolina ($815,515), New York ($790,344), Wisconsin ($726,251), Arizona ($496,755), Tennessee ($449,011), Virginia ($308,006).

Who usually wins

Nonprofits received 93% of the money, colleges and universities 6.3%.

Recipient typeAwardsAmountShare
Nonprofits11$82.7 million93%
Colleges and universities22$5.6 million6.3%
Other3$610,1910.7%

By state

4 states have a page for this program: those that received at least $1 million or 10 awards. They are Minnesota, California, Massachusetts and Pennsylvania.

Grants by recipient's state, fiscal 2021 to 2025
StateAwardsAmount
Minnesota2$69.2 million
California8$12.3 million
Massachusetts3$1.8 million
Pennsylvania4$1.0 million
North Carolina2$815,515
New York3$790,344
Wisconsin3$726,251
Arizona2$496,755
Tennessee1$449,011
Virginia1$308,006
Missouri1$295,450
Texas2$236,937
Colorado1$116,625
Alabama1$111,375
South Carolina1$107,270
Utah1$106,852

Award amounts are federal obligations reported to USAspending.gov for fiscal 2021 to 2025; see how our data works.