RFA-TS-22-001: Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
Closed
This grant is closed. A newer notice from the same program is forecast: Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) (RFA-TS-27-018). Status: Expected deadline February 1, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2022.
Centers for Disease Control and Prevention - ERA offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments, tribes and businesses. It expected to make about 8 awards worth $7.5 million in total. Applications closed on April 22, 2022.
From the official notice on Grants.gov, last changed April 18, 2022. Checked November 7, 2026.
- Award ceiling$500,000
- Total funding$7.5 million
- Expected awards8
- Cost sharingNot required
- Funding typeGrant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| RFA-TS-27-018 | July 8, 2026 | Expected deadline February 1, 2027 | Forecast |
| RFA-TS-26-165 | May 11, 2026 | Closed June 10, 2026 | Closed |
| RFA-TS-25-036 | August 1, 2024 | Closed November 4, 2024 | Closed |
| RFA-TS-24-010 | August 1, 2023 | Closed December 19, 2023 | Closed |
| RFA-TS-23-001 | September 30, 2022 | Closed January 5, 2023 | Closed |
| RFA-TS-21-001 | January 8, 2021 | Closed March 29, 2021 | Closed |
Key dates
| Posted | February 14, 2022 |
|---|---|
| Deadline | April 22, 2022 |
| Archived by Grants.gov | May 22, 2022 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes and businesses.
All 14 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
See Section III. Eligibility Information.
Is this a realistic fit?
- Past Health Program for Toxic Substances and Disease Registry awards averaged $2.9 million; this notice allows up to $500,000 per award.
- Most of the program's money (73% over five years) went to state and local governments.
- No cost sharing or match is required.
What the grant funds
The Centers for Disease Control/Agency for Toxic Substances and Disease Registry (CDC/ATSDR) is seeking investigator-initiated research that will further the understanding of potential risk factors for Amyotrophic Lateral Sclerosis (ALS), while supporting the National ALS Registry"s mission. The National ALS Registry"s goals are to estimate the number of new ALS cases each year, estimate the number of people who have ALS at a specific point in time, better understand who gets ALS, and identify what contributing factors, including environmental, may affect ALS. CDC/ATSDR is seeking investigator-initiated research that will identify and evaluate risk factors contributing to ALS, with preferred focus in this Notice of Funding Opportunity on factors related to military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents. Research proposals on preferred topics can be funded under one of two funding options, Funding Option A or Funding Option B. Funding Option A is intended to support ALS risk factor research investigations that have an existing, well substantiated evidence base and would benefit from strengthened rigorous evaluation. Funding Option B is intended to support novel ALS risk factor research investigations that may or may not have an existing evidence base foundation base, may be supported by limited and insuffiicient preliminary research, and are exploratory and developmental in nature.
Who has won Health Program for Toxic Substances and Disease Registry grants before
From fiscal 2021 to 2025, Health Program for Toxic Substances and Disease Registry (93.161) awarded $20.4 million across 7 grant awards, an average of $2.9 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| American Academy of Pediatrics | Illinois | 1 | $15.0 million |
| Regents of the University of Michigan | Michigan | 2 | $1.9 million |
| Karolinska Institutet | 1 | $1.5 million | |
| Public Health Institute | California | 1 | $1.2 million |
| President and Fellows of Harvard College | Massachusetts | 1 | $860,394 |
Applying now
This notice no longer takes applications. Apply under the newer notice, RFA-TS-27-018, which is forecast.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-TS-22-001 still open?
No. It closed on April 22, 2022. A newer notice is forecast: RFA-TS-27-018, expected deadline February 1, 2027.
Who can apply for Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)?
Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments, tribes and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)?
Closed April 22, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each. About $7.5 million in total across about 8 awards.
Who has won Health Program for Toxic Substances and Disease Registry grants before?
The largest recipients over five fiscal years were American Academy of Pediatrics, Regents of the University of Michigan, Karolinska Institutet. The program made 7 awards worth $20.4 million in that time.
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