RFA-TS-21-001: Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
Closed
This grant is closed. A newer notice from the same program is forecast: Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) (RFA-TS-27-018). Status: Expected deadline February 1, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2021.
Centers for Disease Control and Prevention - ERA offered grants of up to $500,000 to nonprofits, colleges and universities, state and local governments and tribes. It expected to make about 5 awards worth $7.5 million in total. Applications closed on March 29, 2021.
From the official notice on Grants.gov, last changed March 23, 2021. Checked November 7, 2026.
- Award ceiling$500,000
- Total funding$7.5 million
- Expected awards5
- Cost sharingNot required
- Funding typeGrant
Other notices with this title
| Notice | Posted | Deadline | Status |
|---|---|---|---|
| RFA-TS-27-018 | July 8, 2026 | Expected deadline February 1, 2027 | Forecast |
| RFA-TS-26-165 | May 11, 2026 | Closed June 10, 2026 | Closed |
| RFA-TS-25-036 | August 1, 2024 | Closed November 4, 2024 | Closed |
| RFA-TS-24-010 | August 1, 2023 | Closed December 19, 2023 | Closed |
| RFA-TS-23-001 | September 30, 2022 | Closed January 5, 2023 | Closed |
| RFA-TS-22-001 | February 14, 2022 | Closed April 22, 2022 | Closed |
Key dates
| Posted | January 8, 2021 |
|---|---|
| Deadline | March 29, 2021 |
| Archived by Grants.gov | April 28, 2021 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments and tribes.
All 13 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Eligibility Category:The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education: Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Native American tribal organizations (other than Federally recognized tribal governments), Faith-based or Community-based Organizations, Regional Organizations Bona Fide Agents: A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with "Other Attachment Forms." Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long-term research or development need which cannot be met as effectively by an agency's existing in-house or contractor resources. FFRDC's enable agencies to use private sectorresources to accomplish tasks that are integral to the mission and operation of the sponsoring agency. For more information on FFRDCs, go to https://dap.dau.mil/acquipedia/Pages/ArticleDetails.aspx?aid=5e3079b8-44f2-43df-a0e7-9f379e8c48ed Foreign Organizations are eligible to apply.
Is this a realistic fit?
- Past Health Program for Toxic Substances and Disease Registry awards averaged $2.9 million; this notice allows up to $500,000 per award.
- Most of the program's money (73% over five years) went to state and local governments.
- No cost sharing or match is required.
What the grant funds
The Agency for Toxic Substances and Disease Registry (ATSDR) is seeking investigator initiated research that will further the understanding of potential risk factors for ALS, while supporting the National ALS Registry's mission. The National ALS Registry's goals are to estimate the number of new ALS cases each year, estimate the number of people who have ALS at a specific point in time, better understand who gets ALS, and identify what contributing factors, including environmental, may affect ALS. ATSDR is seeking investigator-initiated research that will identify and evaluate risk factors contributing to ALS, with preferred focus in this Notice of Funding Opportunity on factors related to military service, contact sports, traumatic brain injury, neuroinflammation and infectious agents.
Who has won Health Program for Toxic Substances and Disease Registry grants before
From fiscal 2021 to 2025, Health Program for Toxic Substances and Disease Registry (93.161) awarded $20.4 million across 7 grant awards, an average of $2.9 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| American Academy of Pediatrics | Illinois | 1 | $15.0 million |
| Regents of the University of Michigan | Michigan | 2 | $1.9 million |
| Karolinska Institutet | 1 | $1.5 million | |
| Public Health Institute | California | 1 | $1.2 million |
| President and Fellows of Harvard College | Massachusetts | 1 | $860,394 |
Applying now
This notice no longer takes applications. Apply under the newer notice, RFA-TS-27-018, which is forecast.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-TS-21-001 still open?
No. It closed on March 29, 2021. A newer notice is forecast: RFA-TS-27-018, expected deadline February 1, 2027.
Who can apply for Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)?
Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments and tribes. The notice adds further conditions, so read its eligibility section.
What is the deadline for Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)?
Closed March 29, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $500,000 each. About $7.5 million in total across about 5 awards.
Who has won Health Program for Toxic Substances and Disease Registry grants before?
The largest recipients over five fiscal years were American Academy of Pediatrics, Regents of the University of Michigan, Karolinska Institutet. The program made 7 awards worth $20.4 million in that time.
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