RFA-RM-23-010: Limited Competition: Molecular Transducers of Physical Activity Clinical Centers (U01 Clinical Trial Required)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants to the applicants described in the notice. Applications closed on May 15, 2023.
From the official notice on Grants.gov, last changed March 22, 2023. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU01
- Clinical trialsRequired
- Funded byNIAMS
- Median yearly award$1.3 million
- Typical project length10.5 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-RM-23-010 were run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, 6 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-RM-23-010 in the NIH Guide.
Key dates
| Posted | March 22, 2023 |
|---|---|
| Deadline | May 15, 2023 |
| Archived by Grants.gov | June 20, 2023 |
Who can apply
This opportunity was open to the applicants described in the notice.
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. See Full Announcement for additional details on eligibility.
Is this a realistic fit?
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This Limited Competition Funding Opportunity Announcement (NOFO) invites applications to complete recruitment and follow-up for the Molecular Transducers of Physical Activity Consortia (MoTrPAC) clinical studies, including finishing mechanistic randomized controlled trials of sedentary adults and children and observational studies of highly active adults and children. Only current MoTrPAC clinical center awardees are eligible to apply. These will be collaborative cooperative agreements and applicants are expected to use the uniform IRB approved protocol and have research approaches in accordance with DSMB guidance for analysis of clinical trial data.
Funded under RFA-RM-23-010 so far
NIH funded 6 projects under RFA-RM-23-010 in fiscal 2023 to 2024, at 6 institutions. The median yearly award was $1.3 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Molecular Transducers of Physical Activity Consortium - Colorado Clinical Center | University of Colorado Denver | 2024 | $1.1 million |
| Molecular Transducers of Physical Activity Consortium Adult Clinical Center | Cedars-Sinai Medical Center | 2024 | $2.0 million |
| Molecular Transducers of Physical Activity Consortium (MoTrPAC): Pediatric Clinical Center | University of California-Irvine | 2024 | $747,994 |
| Pennington MoTrPAC Adults - Renewal | LSU Pennington Biomedical Research Ctr | 2024 | $602,006 |
| The Exercise and Physical Activity Collaborative Team (ExPACT): A MoTrPAC Clinical Center | Ball State University | 2024 | $1.1 million |
| Molecular Transducers of Physical Activity and Health: NC Consortium Clinical Site | Duke University | 2024 | $1.1 million |
Who has won Trans-NIH Research Support grants before
From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Duke University | North Carolina | 66 | $219 million |
| The Leland Stanford Junior University | California | 104 | $176 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 82 | $154 million |
| The Johns Hopkins University | Maryland | 95 | $152 million |
| Yale Univ | Connecticut | 85 | $149 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-RM-23-010 still open?
No. It closed on May 15, 2023.
Who can apply for Limited Competition: Molecular Transducers of Physical Activity Clinical Centers (U01 Clinical Trial Required)?
National Institutes of Health accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.
What is the deadline for Limited Competition: Molecular Transducers of Physical Activity Clinical Centers (U01 Clinical Trial Required)?
Closed May 15, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-RM-23-010?
NIH RePORTER lists 6 projects funded under RFA-RM-23-010 in fiscal 2023 to 2024, at 6 institutions. The most were at University of Colorado Denver, Cedars-Sinai Medical Center, University of California-Irvine.
Who has won Trans-NIH Research Support grants before?
The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.
Similar open grants
- Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
- Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
- Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
- Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)
- Canine Cancer Immunotherapy Network (K9CIN; U01 Clinical Trial Not Allowed)
- Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional)