RFA-RM-21-027: The Human BioMolecular Atlas Program (HuBMAP) Demonstration Project (U01 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 19, 2021.
From the official notice on Grants.gov, last changed September 10, 2021. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU01
- Clinical trialsNot allowed
- Funded byNHLBI, NHGRI, NICHD
- Median yearly award$478,659
- Typical project length4.5 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-RM-21-027 were run by National Heart Lung and Blood Institute (NHLBI, 2 projects), National Human Genome Research Institute (NHGRI, 1 project) and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-RM-21-027 in the NIH Guide.
Key dates
| Posted | September 10, 2021 |
|---|---|
| Deadline | November 19, 2021 |
| Archived by Grants.gov | December 25, 2021 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Most of the program's money (72% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The goal of this funding opportunity announcement is to solicit applications that will creatively use datasets and resources from the Human BioMolecular Atlas Program (HuBMAP: https://commonfund.nih.gov/hubmap) to demonstrate their use to address significant biomedical and biological questions. Projects are expected to work closely with the other funded projects as part of the HuBMAP Consortium to provide specific and actionable feedback, validations, tools, software and other resources back to the consortium.
Funded under RFA-RM-21-027 so far
NIH funded 4 projects under RFA-RM-21-027 in fiscal 2022 to 2025, at 4 institutions. The median yearly award was $478,659.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Thinking outside the cell: Leveraging HuBMAP data to build the human ECM atlas | University of Illinois at Chicago | 2025 | $465,000 |
| Reverse Engineering the Extracellular Neighborhood to Support the Functional Tissue Unit: A Use Case to Restore Ovarian Function | Lurie Children's Hospital of Chicago | 2025 | $387,310 |
| Novel biological insights by utilizing mitochondrial genome information from HuBMAP resources | Children's Hosp of Philadelphia | 2025 | $492,318 |
| Identifying the organotypic and disease-specific vascular cell populations by integrating single cell data with polygenic risk | Brigham and Women's Hospital | 2025 | $526,267 |
Who has won Trans-NIH Research Support grants before
From fiscal 2021 to 2025, Trans-NIH Research Support (93.310) awarded $5.9 billion across 4,433 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Duke University | North Carolina | 66 | $219 million |
| The Leland Stanford Junior University | California | 104 | $176 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 82 | $154 million |
| The Johns Hopkins University | Maryland | 95 | $152 million |
| Yale Univ | Connecticut | 85 | $149 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-RM-21-027 still open?
No. It closed on November 19, 2021.
Who can apply for The Human BioMolecular Atlas Program (HuBMAP) Demonstration Project (U01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for The Human BioMolecular Atlas Program (HuBMAP) Demonstration Project (U01 Clinical Trial Not Allowed)?
Closed November 19, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-RM-21-027?
NIH RePORTER lists 4 projects funded under RFA-RM-21-027 in fiscal 2022 to 2025, at 4 institutions. The most were at University of Illinois at Chicago, Lurie Children's Hospital of Chicago, Children's Hosp of Philadelphia.
Who has won Trans-NIH Research Support grants before?
The largest recipients over five fiscal years were Duke University, The Leland Stanford Junior University, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 4,433 awards worth $5.9 billion in that time.
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