Well Told Grants

Grants / Department of Health and Human Services / Centers for Disease Control and Prevention - ERA

RFA-PS-25-113: Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances

Closed Closed February 20, 2025 Opportunity RFA-PS-25-113

This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2024.

Centers for Disease Control and Prevention - ERA offered grants of up to $475,000 (at least $350,000) to nonprofits, colleges and universities, state and local governments, tribes and businesses. It expected to make about 2 awards worth $2.9 million in total. Applications closed on February 20, 2025.

From the official notice on Grants.gov, last changed December 16, 2024. Checked November 7, 2026.

Key dates

PostedDecember 16, 2024
DeadlineFebruary 20, 2025
Archived by Grants.govMarch 22, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes and businesses.

All 13 applicant types the notice lists

N/A

More grants for nonprofits, colleges and universities, state and local governments, tribes, businesses.

Is this a realistic fit?

What the grant funds

The purpose of this Notice of Funding Opportunity (NOFO) is to support pilot research to develop and test behavioral implementation strategies for biomedical interventions (e.g., oral PrEP, condoms) to improve HIV and STI prevention implementation among disproportionately affected populations, especially Black/African American (Black) and Hispanic/Latino (Hispanic) gay, bisexual, and other men who have sex with men (MSM) without HIV who report substance use (drug or alcohol). The study design and sample size should meet minimum requirements for consideration of the CDC Compendium of Best Evidence (https://www.cdc.gov/hivpartners/php/compendium/) and thus may have the potential for future CDC HIV prevention funding implementation in jurisdictions around the United States. The applicants should have access to research participants in priority jurisdictions outlined in Ending the HIV Epidemic in the United States (EHE), in support of the goals of EHE (Ending the HIV Epidemic in the US (EHE) | EHE Initiative | CDC), the HIV National Strategic Plan for the United States: A Roadmap to End the HIV Epidemic (2021-2025) (https://www.cdc.gov/nchhstp/media/pdfs/2024/08/hiv-national-strategic-plan-2021-2025.pdf), and other federal prevention planning efforts.

Category: Health.

Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before

From fiscal 2021 to 2025, Prevention of Disease, Disability, and Death by Infectious Diseases (93.084) awarded $241 million across 128 grant awards, an average of $1.9 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
Puerto Rico Science, Technology, and Research TrustPuerto Rico4$14.5 million
Massachusetts Department of Public HealthMassachusetts1$11.6 million
Emory UniversityGeorgia3$11.5 million
Uganda Virus Research Institute1$8.7 million
Ponce Medical School Foundation IncPuerto Rico2$8.7 million

Top states: Massachusetts ($26.4 million), Puerto Rico ($23.2 million), California ($22.9 million), Georgia ($20.0 million), Maryland ($14.0 million).

Applying now

This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-PS-25-113 still open?

No. It closed on February 20, 2025. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.

Who can apply for Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances?

Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments, tribes and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances?

Closed February 20, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

How much funding is available?

Awards of up to $475,000 each. About $2.9 million in total across about 2 awards.

Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before?

The largest recipients over five fiscal years were Puerto Rico Science, Technology, and Research Trust, Massachusetts Department of Public Health, Emory University. The program made 128 awards worth $241 million in that time.

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