RFA-PS-25-113: Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances
Closed
This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2024.
Centers for Disease Control and Prevention - ERA offered grants of up to $475,000 (at least $350,000) to nonprofits, colleges and universities, state and local governments, tribes and businesses. It expected to make about 2 awards worth $2.9 million in total. Applications closed on February 20, 2025.
From the official notice on Grants.gov, last changed December 16, 2024. Checked November 7, 2026.
- Award ceiling$475,000
- Award floor$350,000
- Total funding$2.9 million
- Expected awards2
- Cost sharingNot required
- Funding typeCooperative Agreement
Key dates
| Posted | December 16, 2024 |
|---|---|
| Deadline | February 20, 2025 |
| Archived by Grants.gov | March 22, 2025 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes and businesses.
All 13 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
N/A
Is this a realistic fit?
- Past Prevention of Disease, Disability, and Death by Infectious Diseases awards averaged $1.9 million; this notice allows up to $475,000 per award.
- No cost sharing or match is required.
What the grant funds
The purpose of this Notice of Funding Opportunity (NOFO) is to support pilot research to develop and test behavioral implementation strategies for biomedical interventions (e.g., oral PrEP, condoms) to improve HIV and STI prevention implementation among disproportionately affected populations, especially Black/African American (Black) and Hispanic/Latino (Hispanic) gay, bisexual, and other men who have sex with men (MSM) without HIV who report substance use (drug or alcohol). The study design and sample size should meet minimum requirements for consideration of the CDC Compendium of Best Evidence (https://www.cdc.gov/hivpartners/php/compendium/) and thus may have the potential for future CDC HIV prevention funding implementation in jurisdictions around the United States. The applicants should have access to research participants in priority jurisdictions outlined in Ending the HIV Epidemic in the United States (EHE), in support of the goals of EHE (Ending the HIV Epidemic in the US (EHE) | EHE Initiative | CDC), the HIV National Strategic Plan for the United States: A Roadmap to End the HIV Epidemic (2021-2025) (https://www.cdc.gov/nchhstp/media/pdfs/2024/08/hiv-national-strategic-plan-2021-2025.pdf), and other federal prevention planning efforts.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before
From fiscal 2021 to 2025, Prevention of Disease, Disability, and Death by Infectious Diseases (93.084) awarded $241 million across 128 grant awards, an average of $1.9 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Puerto Rico Science, Technology, and Research Trust | Puerto Rico | 4 | $14.5 million |
| Massachusetts Department of Public Health | Massachusetts | 1 | $11.6 million |
| Emory University | Georgia | 3 | $11.5 million |
| Uganda Virus Research Institute | 1 | $8.7 million | |
| Ponce Medical School Foundation Inc | Puerto Rico | 2 | $8.7 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-PS-25-113 still open?
No. It closed on February 20, 2025. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.
Who can apply for Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances?
Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments, tribes and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Develop and Test HIV Prevention Interventions for Black and Hispanic Gay, Bisexual, and Other Men Who Have Sex with Men Who Use Substances?
Closed February 20, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $475,000 each. About $2.9 million in total across about 2 awards.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before?
The largest recipients over five fiscal years were Puerto Rico Science, Technology, and Research Trust, Massachusetts Department of Public Health, Emory University. The program made 128 awards worth $241 million in that time.
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