RFA-PS-22-001: Implementing Pre-exposure Prophylaxis for HIV Prevention in Syringe Service Programs
Closed
This grant is closed. A newer notice from the same program is open now: NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100). Status: Due dates in the notice, expires April 5, 2027. It is in our archive of Centers for Disease Control and Prevention - ERA notices from 2021.
Centers for Disease Control and Prevention - ERA offered grants of up to $625,000 (at least $500,000) to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make one award worth $2.5 million in total. Applications closed on January 18, 2022.
From the official notice on Grants.gov, last changed October 28, 2021. Checked November 7, 2026.
- Award ceiling$625,000
- Award floor$500,000
- Total funding$2.5 million
- Expected awards1
- Cost sharingNot required
- Funding typeCooperative Agreement
Key dates
| Posted | October 28, 2021 |
|---|---|
| Deadline | January 18, 2022 |
| Archived by Grants.gov | March 18, 2022 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education: Hispanic-serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Nonprofits (Other than Institutions of Higher Education) Eligible Agencies of the Federal Government Faith-based or Community-based Organizations U.S. Territory or Possession Regional Organizations Bona Fide Agents: A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with "Other Attachment Forms" when submitting via https://www.grants.gov Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long-term research or development need which cannot be met as effectively by an agency’s existing in-house or contractor resources. FFRDC’s enable agencies to use private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring agency. For more information on FFRDCs, go to https://gov.ecfr.io/cgi-bin/searchECFR
Is this a realistic fit?
- No cost sharing or match is required.
What the grant funds
The purpose of this Notice of Funding Opportunity (NOFO) is to support implementation research on combining HIV prevention modalities to add navigation for HIV pre-exposure prophylaxis (PrEP) at syringe service programs (SSPs) for people who inject drugs (PWID). The recipient should be an organization or institution that includes or partners with multiple and diverse SSPs. CDC is interested in increasing PrEP care through SSPs by incorporating more PrEP navigation and support into standard processes. The NOFO seeks effectiveness-implementation research on the acceptability and feasibility of a navigator-enhanced PWID PrEP service bundle at SSPs and optimizing it for initiation and retention in PrEP care among adult PWID. Applied research resulting from this funding is expected to strengthen combined HIV prevention for PWID and is aligned with the HIV National Strategic Plan (2021-2025) and the Ending the HIV Epidemic in the U.S. (EHE) initiative “Prevent” Pillar.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before
From fiscal 2021 to 2025, Prevention of Disease, Disability, and Death by Infectious Diseases (93.084) awarded $241 million across 128 grant awards, an average of $1.9 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Puerto Rico Science, Technology, and Research Trust | Puerto Rico | 4 | $14.5 million |
| Massachusetts Department of Public Health | Massachusetts | 1 | $11.6 million |
| Emory University | Georgia | 3 | $11.5 million |
| Uganda Virus Research Institute | 1 | $8.7 million | |
| Ponce Medical School Foundation Inc | Puerto Rico | 2 | $8.7 million |
Who has won HIV Demonstration, Research, Public and Professional Education Projects grants before
From fiscal 2021 to 2025, HIV Demonstration, Research, Public and Professional Education Projects (93.941) awarded $42.1 million across 21 grant awards, an average of $2.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Research Foundation of the City University of New York | New York | 1 | $6.0 million |
| Ann & Robert H Lurie Childrens Hospital of Chicago | Illinois | 1 | $6.0 million |
| Vanderbilt University Medical Center | Tennessee | 1 | $5.9 million |
| The Trustees of Columbia University in the City of New York | New York | 1 | $5.2 million |
| Florida State University | Florida | 1 | $4.6 million |
Applying now
This notice no longer takes applications. Apply under the newer notice, PA-27-100, which is open now.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-PS-22-001 still open?
No. It closed on January 18, 2022. A newer notice is open: PA-27-100, due dates in the notice, expires April 5, 2027.
Who can apply for Implementing Pre-exposure Prophylaxis for HIV Prevention in Syringe Service Programs?
Centers for Disease Control and Prevention - ERA accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Implementing Pre-exposure Prophylaxis for HIV Prevention in Syringe Service Programs?
Closed January 18, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $625,000 each. About $2.5 million in total for one award.
Who has won Prevention of Disease, Disability, and Death by Infectious Diseases grants before?
The largest recipients over five fiscal years were Puerto Rico Science, Technology, and Research Trust, Massachusetts Department of Public Health, Emory University. The program made 128 awards worth $241 million in that time.
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