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Grants / Department of Health and Human Services / National Institutes of Health

RFA-OD-22-013: Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)

Closed Closed September 25, 2025 Opportunity RFA-OD-22-013

This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2022.

National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on September 25, 2025.

From the official notice on Grants.gov, last changed May 21, 2025. Checked November 7, 2026.

About this NIH notice

Projects funded under RFA-OD-22-013 were run by NIH Office of the Director (OD, 31 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.

Application due dates, page limits and budget limits are set in the notice. Read RFA-OD-22-013 in the NIH Guide.

Key dates

PostedSeptember 9, 2022
DeadlineSeptember 25, 2025
Archived by Grants.govOctober 25, 2025

Who can apply

This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

All 15 applicant types the notice lists

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing or improving animal models of human diseases; improving access to information about or generated from the use of animal models of human disease; or improving diagnosis and control of diseases of laboratory animals. The animal models, related materials, or technological tools developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact multiple body systems in order to align with the ORIPs NIH-wide mission and programs. Applications must describe the need for and the potential impact of the proposed resources on the research community across a range of scientific disciplines supported by multiple NIH ICs. Applications to develop models that relate strictly to a specific disease or a select area of research or that do not have a broad impact on the NIH-wide research community will not be considered acceptable. Projects that predominantly address the research interests of one NIH IC but are only peripherally related to the research interests of other ICs will also not be acceptable for this funding opportunity announcement (FOA).

Category: Health.

Funded under RFA-OD-22-013 so far

NIH funded 31 projects under RFA-OD-22-013 in fiscal 2023 to 2026, at 28 institutions. The median yearly award was $771,673.

Most projects: Univ of Massachusetts Med Sch Worcester (Massachusetts), 2, Medical College of Wisconsin (Wisconsin), 2, Iowa State University (Iowa), 2, La Jolla Institute for Immunology (California), 1, Marine Biological Laboratory (Massachusetts), 1.

Recently funded projects
ProjectInstitutionFiscal yearAward
Next Generation Crispr Ready, HLA Class I and II Transgenic Mouse Platform R24La Jolla Institute for Immunology2026$911,668
Xenopus Mutant Resource R24Marine Biological Laboratory2026$769,186
Comprehensive Resource for the Drosophila 4th chromosome R24Arizona State University-Tempe Campus2026$730,631
An engineered protein tag resource for live imaging and functional studies in zebrafish R24University of Pennsylvania2026$812,443
Neotropical Primate Reagent Resource R24Univ of Massachusetts Med Sch Worcester2026$587,934
Provision of HLA-transgenic fetal pig thymus for human immune system mouse construction R24Columbia University Health Sciences2026$814,060
Enabling AI-based Mouse Genetic Discovery R24Stanford University2026$730,534
Safeguarding Genetic Resources of Aquatic Biomedical Models R24Louisiana State Univ Agricultural Center2026$618,534

From NIH RePORTER, which lists each project once per fiscal year it was funded. Amounts are the yearly award.

Who has won Research Infrastructure Programs grants before

From fiscal 2021 to 2025, Research Infrastructure Programs (93.351) awarded $1.4 billion across 1,102 grant awards, an average of $1.3 million per award.

Largest recipients, fiscal 2021 to 2025
RecipientStateAwardsAmount
University of California, DavisCalifornia27$102 million
Oregon Health & Science UniversityOregon18$92.1 million
University of WashingtonWashington7$79.5 million
Emory UniversityGeorgia14$78.3 million
The Administrators of Tulane Educational FundLouisiana10$68.0 million

Top states: California ($183 million), Texas ($127 million), Oregon ($111 million), Massachusetts ($90.4 million), Washington ($87.3 million).

Applying now

This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.

The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.

Questions people ask

Is RFA-OD-22-013 still open?

No. It closed on September 25, 2025.

Who can apply for Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)?

Closed September 25, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

Who has been funded under RFA-OD-22-013?

NIH RePORTER lists 31 projects funded under RFA-OD-22-013 in fiscal 2023 to 2026, at 28 institutions. The most were at Univ of Massachusetts Med Sch Worcester, Medical College of Wisconsin, Iowa State University.

Who has won Research Infrastructure Programs grants before?

The largest recipients over five fiscal years were University of California, Davis, Oregon Health & Science University, University of Washington. The program made 1,102 awards worth $1.4 billion in that time.

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