RFA-HL-26-007: Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in GEnomics Cohort (B2B CHANGE Cohort) Data Coordinating Center (U01 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2025.
National Institutes of Health offered grants of up to $4.0 million to colleges and universities. Applications closed on March 18, 2025.
From the official notice on Grants.gov, last changed January 10, 2025. Checked November 7, 2026.
- Award ceiling$4.0 million
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeB2B / U01
- Clinical trialsNot allowed
- Funded byNHLBI
- Median yearly award$6.5 million
- Typical project length6 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-HL-26-007 were run by National Heart Lung and Blood Institute (NHLBI, 1 project). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-HL-26-007 in the NIH Guide.
Key dates
| Posted | January 10, 2025 |
|---|---|
| Deadline | March 18, 2025 |
| Archived by Grants.gov | April 23, 2025 |
Who can apply
This opportunity was open to colleges and universities.
- Public and State controlled institutions of higher education
Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. Only the following applicant is eligible to apply for this single source funding: Cincinnati Children's Hospital Medical Center.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $6.5 million; it allows up to $4.0 million per award.
- Most of the program's money (70% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
The B2B Pediatric Cardiac Genomics Consortium (PCGC) (http://www.benchtobassinet.com/) will evolve to the B2B CHANGE Cohort (Congenital Heart disease Advancing New understanding in GEnomics). The B2B CHANGE Cohorts mission will be to conduct long-term clinical follow up on participants from the original PCGC Cohort, to perform deeper cohort phenotyping and to support investigators in applying for funding to conduct multi-center, collaborative ancillary studies to further understand how genetic variants relate to clinical outcomes. The Administrative Coordinating Center (ACC) will serve to lead and advance data and resource management and sharing, and coordinate critical data collection and participant outreach efforts at the clinical research sites. The ACC will work in a collaborative fashion with site PIs, as well as the broader congenital heart disease (CHD) research community.
Funded under RFA-HL-26-007 so far
NIH funded 1 project under RFA-HL-26-007 in fiscal 2026, at 1 institution. The median yearly award was $6.5 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Data Coordinating Center: B2B CHANGE Cohort | Cincinnati Childrens Hosp Med Ctr | 2026 | $6.5 million |
Who has won Cardiovascular Diseases Research grants before
From fiscal 2021 to 2025, Cardiovascular Diseases Research (93.837) awarded $15 billion across 11,798 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Trustees of the University of Pennsylvania | Pennsylvania | 313 | $380 million |
| Brigham & Womens Hospital Inc | Massachusetts | 274 | $374 million |
| Regents of the University of Michigan | Michigan | 277 | $355 million |
| The Trustees of Columbia University in the City of New York | New York | 207 | $335 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 295 | $320 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-HL-26-007 still open?
No. It closed on March 18, 2025.
Who can apply for Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in GEnomics Cohort (B2B CHANGE Cohort) Data Coordinating Center (U01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from colleges and universities. The notice adds further conditions, so read its eligibility section.
What is the deadline for Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in GEnomics Cohort (B2B CHANGE Cohort) Data Coordinating Center (U01 Clinical Trial Not Allowed)?
Closed March 18, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $4.0 million each.
Who has been funded under RFA-HL-26-007?
NIH RePORTER lists 1 project funded under RFA-HL-26-007 in fiscal 2026, at 1 institution.
Who has won Cardiovascular Diseases Research grants before?
The largest recipients over five fiscal years were The Trustees of the University of Pennsylvania, Brigham & Womens Hospital Inc, Regents of the University of Michigan. The program made 11,798 awards worth $15 billion in that time.
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