RFA-HG-25-005: Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2024.
National Institutes of Health offered grants of up to $125,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $125,000 in total. Applications closed on February 15, 2026.
From the official notice on Grants.gov, last changed November 18, 2024. Checked November 7, 2026.
- Award ceiling$125,000
- Total funding$125,000
- Cost sharingNot required
- Funding typeGrant
About this NIH notice
- Activity codeR03
- Clinical trialsNot allowed
- Funded byNHGRI
- Median yearly award$412,875
- Typical project length2 years
- R03, Small Grant. A small, short project such as pilot work, a feasibility study, secondary data analysis or a new method, usually for up to two years. Other open R03 notices.
Projects funded under RFA-HG-25-005 were run by National Human Genome Research Institute (NHGRI, 4 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-HG-25-005 in the NIH Guide.
Key dates
| Posted | November 18, 2024 |
|---|---|
| Deadline | February 15, 2026 |
| Archived by Grants.gov | March 23, 2026 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $412,875; it allows up to $125,000 per award.
- Most of the program's money (67% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
To support secondary analysis of AnVIL datasets and increase utilization of the AnVIL platform for small research projects by eliminating the cost barriers new users face. Through this additional analysis, this RFA will illuminate the value of NHGRI datasets for secondary research and the effectiveness of AnVIL to stimulate further discovery.
Funded under RFA-HG-25-005 so far
NIH funded 4 projects under RFA-HG-25-005 in fiscal 2026, at 4 institutions. The median yearly award was $412,875.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| Developing a cCRE-Centric Infrastructure in AnVIL to Characterize Variant Effects on Gene Regulation | Univ of Massachusetts Med Sch Worcester | 2026 | $418,750 |
| Enhancing Reuse of NHGRI Cohort Data with GA4GH Genomic Knowledge Standards | Research Inst Nationwide Children's Hosp | 2026 | $407,000 |
| Expanding our understanding of polygenic disease comorbidity structure: PRSxPheWAS | Vanderbilt University Medical Center | 2026 | $437,500 |
| Variability in organization and expression of multi-copy genes on human sex chromosomes | The Pennsylvania State University | 2026 | $393,250 |
Who has won Human Genome Research grants before
From fiscal 2021 to 2025, Human Genome Research (93.172) awarded $2.2 billion across 1,255 grant awards, an average of $1.7 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Leland Stanford Junior University | California | 59 | $153 million |
| University of Washington | Washington | 46 | $123 million |
| The Broad Institute, Inc | Massachusetts | 22 | $119 million |
| University of California Santa Cruz | California | 17 | $64.7 million |
| Baylor College of Medicine | Texas | 24 | $62.9 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-HG-25-005 still open?
No. It closed on February 15, 2026.
Who can apply for Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)?
Closed February 15, 2026. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $125,000 each. About $125,000 in total.
Who has been funded under RFA-HG-25-005?
NIH RePORTER lists 4 projects funded under RFA-HG-25-005 in fiscal 2026, at 4 institutions. The most were at Univ of Massachusetts Med Sch Worcester, Research Inst Nationwide Children's Hosp, Vanderbilt University Medical Center.
Who has won Human Genome Research grants before?
The largest recipients over five fiscal years were The Leland Stanford Junior University, University of Washington, The Broad Institute, Inc. The program made 1,255 awards worth $2.2 billion in that time.
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