RFA-EY-21-004: Ocular Surface Innervation from Cell Types to Circuit Functions (U01 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on March 7, 2022.
From the official notice on Grants.gov, last changed December 10, 2021. Checked November 7, 2026.
- Award amountsNot given on Grants.gov
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU01
- Clinical trialsNot allowed
- Funded byNEI
- Median yearly award$1.2 million
- Typical project length5 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-EY-21-004 were run by National Eye Institute (NEI, 8 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-EY-21-004 in the NIH Guide.
Key dates
| Posted | December 10, 2021 |
|---|---|
| Deadline | March 7, 2022 |
| Archived by Grants.gov | April 12, 2022 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Most of the program's money (76% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This Funding Opportunity Announcement (FOA) aims to identify and support collaborative projects that will comprehensively delineate ocular surface innervation from corneal sensation to pain circuits and tearing reflexes. The Request for Applications (RFA) aims to explore this system at three levels of analysis: morphologic, molecular, and functional. Successful projects will incorporate and integrate at least two of these levels of analysis, and ideally all three. Collaborative multi-disciplinary teams are expected with investigators having complementary areas of expertise. The premise of this FOA is that such basic biology will facilitate a deeper understanding of related pathobiology including neuropathic ocular pain and dry eye disease that will lay a foundation for future translational and clinical research on the anterior segment of the eye.
Funded under RFA-EY-21-004 so far
NIH funded 8 projects under RFA-EY-21-004 in fiscal 2022 to 2026, at 8 institutions. The median yearly award was $1.2 million.
Who has won Vision Research grants before
From fiscal 2021 to 2025, Vision Research (93.867) awarded $3.4 billion across 3,275 grant awards, an average of $1.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The Johns Hopkins University | Maryland | 137 | $139 million |
| The Leland Stanford Junior University | California | 87 | $96.5 million |
| The Regents of the University of California, San Francisco | California | 78 | $89.9 million |
| Duke University | North Carolina | 79 | $75.5 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 57 | $73.9 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-EY-21-004 still open?
No. It closed on March 7, 2022.
Who can apply for Ocular Surface Innervation from Cell Types to Circuit Functions (U01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for Ocular Surface Innervation from Cell Types to Circuit Functions (U01 Clinical Trial Not Allowed)?
Closed March 7, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.
Who has been funded under RFA-EY-21-004?
NIH RePORTER lists 8 projects funded under RFA-EY-21-004 in fiscal 2022 to 2026, at 8 institutions. The most were at Duke University, Boston Children's Hospital, Oregon Health & Science University.
Who has won Vision Research grants before?
The largest recipients over five fiscal years were The Johns Hopkins University, The Leland Stanford Junior University, The Regents of the University of California, San Francisco. The program made 3,275 awards worth $3.4 billion in that time.
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