RFA-DK-22-036: A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2023.
National Institutes of Health offered grants of up to $300,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 15, 2023.
From the official notice on Grants.gov, last changed August 1, 2023. Checked November 7, 2026.
- Award ceiling$300,000
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU01
- Clinical trialsNot allowed
- Funded byNIDDK
- Median yearly award$622,698
- Typical project length5 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-DK-22-036 were run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, 5 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-DK-22-036 in the NIH Guide.
Key dates
| Posted | July 31, 2023 |
|---|---|
| Deadline | November 15, 2023 |
| Archived by Grants.gov | December 21, 2023 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Is this a realistic fit?
- Projects NIH funded under this notice had a median yearly award of $622,698; it allows up to $300,000 per award.
- Most of the program's money (70% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
This FOA invites new applications to participate in the Gut-Brain Communication in Parkinsons Disease (PD) Consortium (GBPDC). The goals of this initiative are 1) to establish a network of individual research projects and a Coordinating Center focused on clinical research; 2) recruitment of sufficient patients and use of standardized protocols to collect data and biospecimens relevant to both neurology and gastroenterology research on PD; 3) share data, biomaterials, models, reagents, resources and methods among projects in the GBPD; and 4) make these publicly available through the Coordinating Center. The objective of this consortium is to accelerate research on the role gastrointestinal (GI) symptoms and changes in gut-brain communication in the initiation and pathogenesis of Parkinsons disease in order to facilitate development and validation of innovative early-phase GI-based diagnostic tools and biomarkers for PD. The research centers of the GBPDC will serve as sites for enrollment of PD patients with and without GI symptoms, patients with GI symptoms considered to be at risk for PD, and healthy age-matched controls for laboratory-based studies on biological samples obtained from these patients. The NIDDK strongly encourages Research on Sex/Gender Differences, Sexual and Gender Minority-Related Research and Race/Ethnic Diversity (see NOT-DK-22-003).
Funded under RFA-DK-22-036 so far
NIH funded 5 projects under RFA-DK-22-036 in fiscal 2024 to 2026, at 5 institutions. The median yearly award was $622,698.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| The Bidirectional Gut-Microbiota-Brain Axis in Parkinson’s disease: integrating mechanistic biomarkers of disease severity and progression | Rush University Medical Center | 2026 | $700,162 |
| Mayo Clinic Consortium for Gut Brain Communication in Parkinson's Disease | Mayo Clinic Rochester | 2026 | $726,297 |
| Role of altered gut immune response in Lewy Body Disease | Stanford University | 2026 | $644,470 |
| A cross-sectional and longitudinal study of gut microbiota in Parkinson's disease | University of Chicago | 2026 | $738,000 |
| A Consortium for Gut-Brain Communication in Parkinson's Disease | Massachusetts General Hospital | 2025 | $600,926 |
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before
From fiscal 2021 to 2025, Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847) awarded $9.6 billion across 7,877 grant awards, an average of $1.2 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Regents of the University of Michigan | Michigan | 273 | $345 million |
| The Trustees of the University of Pennsylvania | Pennsylvania | 187 | $272 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 209 | $238 million |
| The Washington University | Missouri | 187 | $227 million |
| The Regents of the University of California, San Francisco | California | 176 | $208 million |
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-DK-22-036 still open?
No. It closed on November 15, 2023.
Who can apply for A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed)?
Closed November 15, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
Awards of up to $300,000 each.
Who has been funded under RFA-DK-22-036?
NIH RePORTER lists 5 projects funded under RFA-DK-22-036 in fiscal 2024 to 2026, at 5 institutions. The most were at Rush University Medical Center, Mayo Clinic Rochester, Stanford University.
Who has won Diabetes, Digestive, and Kidney Diseases Extramural Research grants before?
The largest recipients over five fiscal years were Regents of the University of Michigan, The Trustees of the University of Pennsylvania, University of Pittsburgh - of the Commonwealth System of Higher Education. The program made 7,877 awards worth $9.6 billion in that time.
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