RFA-DA-21-020: HEAL Initiative: HEALthy Brain and Child Development Study (Collaborative U01- Clinical Trial Not Allowed)
Closed
This grant is closed. Who won this program's grants before is below, and similar open grants are at the end of the page. It is in our archive of National Institutes of Health notices from 2021.
National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $26.0 million in total. Applications closed on March 31, 2021.
From the official notice on Grants.gov, last changed January 11, 2021. Checked November 7, 2026.
- Total funding$26.0 million
- Cost sharingNot required
- Funding typeCooperative Agreement
About this NIH notice
- Activity codeU01
- Clinical trialsNot allowed
- Funded byNIDA
- Median yearly award$1.5 million
- Typical project length5.5 years
- U01, Research Project Cooperative Agreement. Like an R01, but NIH staff are substantially involved in the work. Other open U01 notices.
Projects funded under RFA-DA-21-020 were run by National Institute on Drug Abuse (NIDA, 25 projects). Contact the program officer at the institute that fits your project before you apply; the notice lists them.
Application due dates, page limits and budget limits are set in the notice. Read RFA-DA-21-020 in the NIH Guide.
Key dates
| Posted | January 11, 2021 |
|---|---|
| Deadline | March 31, 2021 |
| Archived by Grants.gov | May 6, 2021 |
Who can apply
This opportunity was open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.
All 15 applicant types the notice lists
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Is this a realistic fit?
- Most of the money in the 7 programs behind this notice (73% over five years) went to colleges and universities.
- No cost sharing or match is required.
What the grant funds
To address critical questions surrounding the long-term impact of substance exposure on child development, the NIH seeks to create a large, diverse cohort of pregnant women, who along with their offspring, will be followed for 10 years. The cohort will consist of mother and baby dyads recruited beginning in the 2nd trimester of pregnancy and through birth; and will include babies exposed pre- or perinatally to prescription and illicit opioids, marijuana, stimulants, alcohol and nicotine. A deep, nuanced understanding of factors that affect a childs health, brain, and behavioral development is expected to emerge from this study, which is an essential first step toward designing policies and interventions that promote well-being and resiliency in children. Applications are sought from qualified researchers with the capacity and expertise to recruit and retain vulnerable populations for studies that will include neuroimaging, cognitive and behavioral assessments along with collection and analysis of biospecimens from mom and baby.
Funded under RFA-DA-21-020 so far
NIH funded 25 projects under RFA-DA-21-020 in fiscal 2021 to 2026, at 25 institutions. The median yearly award was $1.5 million.
| Project | Institution | Fiscal year | Award |
|---|---|---|---|
| 5/24 Healthy Brain and Child Development National Consortium | Boston Children's Hospital | 2026 | $2.3 million |
| 16/24 Healthy Brain and Child Development National Consortium | Univ of Maryland, College Park | 2026 | $1.7 million |
| 1/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium | Arkansas Children's Hospital Res Inst | 2026 | $2.1 million |
| 9/24- Healthy Brain and Child Development National Consortium | Northwestern University | 2026 | $1.6 million |
| 23/24 Healthy Brain and Child Development National Consortium | Washington University | 2026 | $2.0 million |
| 8/24 The Healthy Brain and Child Development National Consortium | New York University School of Medicine | 2026 | $1.9 million |
| 4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium | Cincinnati Childrens Hosp Med Ctr | 2026 | $2.4 million |
| 10/24 Healthy Brain and Child Development National Consortium | OSU Center for Health Sciences | 2026 | $1.3 million |
Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before
From fiscal 2021 to 2025, Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853) awarded $9.1 billion across 8,641 grant awards, an average of $1.0 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| The General Hospital Corporation | Massachusetts | 203 | $288 million |
| The Regents of the University of California, San Francisco | California | 248 | $277 million |
| The Johns Hopkins University | Maryland | 230 | $276 million |
| The Trustees of Columbia University in the City of New York | New York | 188 | $226 million |
| Regents of the University of Michigan | Michigan | 179 | $221 million |
Who has won Mental Health Research Grants grants before
From fiscal 2021 to 2025, Mental Health Research Grants (93.242) awarded $8.8 billion across 6,785 grant awards, an average of $1.3 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 185 | $371 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 200 | $297 million |
| University of California, Los Angeles | California | 176 | $234 million |
| Icahn School of Medicine at Mount Sinai | New York | 144 | $212 million |
| The Washington University | Missouri | 149 | $211 million |
Who has won Drug Use and Addiction Research Programs grants before
From fiscal 2021 to 2025, Drug Use and Addiction Research Programs (93.279) awarded $7.3 billion across 5,071 grant awards, an average of $1.4 million per award.
| Recipient | State | Awards | Amount |
|---|---|---|---|
| Yale Univ | Connecticut | 150 | $305 million |
| The Johns Hopkins University | Maryland | 156 | $262 million |
| University of California, San Diego | California | 120 | $242 million |
| University of Pittsburgh - of the Commonwealth System of Higher Education | Pennsylvania | 100 | $182 million |
| New York University | New York | 62 | $173 million |
Other programs behind this notice
- Alcohol Research Programs
- Environmental Health
- Minority Health and Health Disparities Research
- Discovery and Applied Research for Technological Innovations to Improve Human Health
Applying now
This notice no longer takes applications. Agencies often post the same opportunity again under a new number, so check the program's notices on Grants.gov and the similar open grants below.
The notice on Grants.gov keeps its full text and attachments, which is useful for planning a resubmission.
Questions people ask
Is RFA-DA-21-020 still open?
No. It closed on March 31, 2021.
Who can apply for HEAL Initiative: HEALthy Brain and Child Development Study (Collaborative U01- Clinical Trial Not Allowed)?
National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.
What is the deadline for HEAL Initiative: HEALthy Brain and Child Development Study (Collaborative U01- Clinical Trial Not Allowed)?
Closed March 31, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.
How much funding is available?
About $26.0 million in total.
Who has been funded under RFA-DA-21-020?
NIH RePORTER lists 25 projects funded under RFA-DA-21-020 in fiscal 2021 to 2026, at 25 institutions. The most were at Boston Children's Hospital, Univ of Maryland, College Park, Arkansas Children's Hospital Res Inst.
Who has won Environmental Health grants before?
The largest recipients over five fiscal years were Icahn School of Medicine at Mount Sinai, The Trustees of Columbia University in the City of New York, University of North Carolina at Chapel Hill. The program made 1,980 awards worth $2.1 billion in that time.
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